PHAGE: Therapy, Applications, and Research

The only peer-reviewed journal dedicated to bacteriophage research; Editor-in-Chief @MarthaClokie, Publisher @liebertpub

[PHAGE: Therapy, Applications, and Research @PHAGEJournal]

Our new issue is out!
From Aquaculture to Acinetobacter: Growing the Phage Toolbox
Read more: https://t.co/8eSHGfzwVz

[PHAGE: Therapy, Applications, and Research @PHAGEJournal]

#NewPhageArticle from #Malaysia researchers
Repeated oral administration of a Salmonella Typhimurium phage cocktail over 28 days was well tolerated in mice, with no treatment-related pathological effects reported.
For more: https://t.co/clWFbtzuQw

[PHAGE: Therapy, Applications, and Research @PHAGEJournal]

Novel lytic phage Rocko targets Burkholderia and shows rare stationary‑phase killing at cooler temperatures. Genomically safe but inactive at 37°C, offering promise for biofilm‑focused phage cocktails.
More: https://t.co/ULh25f82iP

[PHAGE: Therapy, Applications, and Research @PHAGEJournal]

Novel lytic phage Rocko targets Burkholderia and shows rare stationary‑phase killing at cooler temperatures. Genomically safe but inactive at 37°C, offering promise for biofilm‑focused phage cocktails.
More: https://t.co/ULh25f82iP

[PHAGE: Therapy, Applications, and Research @PHAGEJournal]

A sensitive method detects Flavobacterium phages at 0.011 PFU/mL, revealing rich phage activity in trout farm water. Big boost for sustainable aquaculture.
Read more & authors are happy to engage further! https://t.co/uc59XgzRK5

[PHAGE: Therapy, Applications, and Research @PHAGEJournal]

Phage‑based tools are advancing AMR control in livestock. A new #ResearchArticle profiles four Escherichia phages with strong stability (10–45°C; 52 weeks) and potent lytic activity in broth + gut fluid.
More: https://t.co/qu7PtVZcLV

[PHAGE: Therapy, Applications, and Research @PHAGEJournal]

Phage therapy shows dose‑dependent power in tilapia, boosting survival, immunity, and tissue recovery. A precise, antibiotic‑free path for aquaculture’s future.
Read more: https://t.co/EV8QpQFUNj

[PHAGE: Therapy, Applications, and Research @PHAGEJournal]

We are deeply saddened to hear about the passing of Dr Elizabeth ‘Betty’ Kutter last week.
We are inviting you all to read a lovely interview with Betty back in 2019 hosted by our Editor-in-Chief, Prof. Martha Clokie. Read here: https://t.co/eD8yxBTcOW

[PHAGE: Therapy, Applications, and Research @PHAGEJournal]

Climate change is reshaping the microscopic world. Rising temps disrupt phage–host dynamics, alter carbon flux, and even influence methane oxidation.

Read this from our latest paper here: https://t.co/5rq6gaedfa

[PHAGE: Therapy, Applications, and Research @PHAGEJournal]

Phages do more than kill bacteria-they shape immune responses. Emerging evidence shows pro‑ and anti‑inflammatory effects, with phagocytosis boosted and inflammation reduced—a rising therapeutic frontier.
Read more: https://t.co/byAP49ShsL

[Viruses MDPI @VirusesMDPI]

🦠 How can bacteriophages improve food safety?

This review examines manufacturing quality, regulatory governance, and a One Health framework to support the safe use of phages as food biocontrol agents.

🔗 https://t.co/fdC0QysZv7

#Bacteriophages #FoodSafety #OneHealth #Virology

[PHAGE: Therapy, Applications, and Research @PHAGEJournal]

Newly isolated phage Ps1.JH exhibits potent lytic activity against MDR P. aeruginosa from diabetic‑foot ulcers. Stable across pH 4–9 and ≤ 60 °C, genetically safe, and depolymerase‑armed, Ps1.JH represents a robust therapeutic candidate. Read: https://t.co/6DlIK4ROME

[PHAGE: Therapy, Applications, and Research @PHAGEJournal]

🧬🧫 DH23 phage infects E. coli in early stationary phase, a rare T7‑like trait. With expanding plaques and a burst size of ~600, it’s a strong candidate for phages targeting chronic or nutrient‑limited infections.
Full paper: https://t.co/icQSyWTXaR

[PHAGE: Therapy, Applications, and Research @PHAGEJournal]

New paper🧬🧫

“As the threat of antibiotic-resistant bacteria like E. faecium increases, understanding the interactions between phages and their host bacteria can be valuable in providing phages as adjunctive therapeutics for infected patients."

Link: https://t.co/o6QK57aMdb

[PHAGE: Therapy, Applications, and Research @PHAGEJournal]

Our June issue is now available🌟

🌱 Phages and climate change

🐟 Aquaculture and livestock production

🧫 Chronic wound pathogens

🏥 Hospital-adapted bacteria

https://t.co/aScdmIyzbt

Read the full editorial here: https://t.co/sTiY6WJ4oK

[PHAGE: Therapy, Applications, and Research @PHAGEJournal]

A new paper from @chinantoinette & colleagues shows Xoo phage vB_XORNC02 is strongly lytic, environmentally stable, and >95% identical to Tsukubavirus XPP1. A promising biocontrol option for bacterial leaf blight.
Read more: https://t.co/eHNqQuRGF9

@jbancla

[PHAGE: Therapy, Applications, and Research @PHAGEJournal]

🧬 New paper: SARS‑CoV‑2 doesn’t just disrupt the microbiome: it reshapes the phageome.
@siddharthstomar & @CsirEvc share their findings showing phage richness skyrockets in infected individuals (79 vs. 28 genera), bacterial diversity drops. Read more: https://t.co/a5q4clT3ux

[PHAGE: Therapy, Applications, and Research @PHAGEJournal]

New paper🧬
This review summarises recent advancements in the field of holins and spanins, membrane-disrupting lysis proteins that essentially act as the “clock” of the phage infection cycle, and potential next-gen therapeutics.

Read the full review here: https://t.co/beSArzjj60

[PHAGE: Therapy, Applications, and Research @PHAGEJournal]

New paper🧫
This paper characterises a novel lytic phage, ɸKP-C01, against a carbapenem-resistant Klebsiella pneumoniae strain , a major threat to global public health and potential for an epidemic.
Read in full here: https://t.co/c5uMMdpkGv

[PHAGE: Therapy, Applications, and Research @PHAGEJournal]

✨New paper
K. pneumoniae persists up to 24 h on hospital surfaces, with persistence at 24°C. Osorio et al. from Columbia show a 3‑phage cocktail delivers ~5‑log killing in 6 h and prevents disinfectant‑linked regrowth.
Read more here: https://t.co/9WSqeIHmUA