@Dr_KatieG1 I love that something approximating this is a requirement of most private sector engineering and science teams, but being a non-shit-show is entirely opt-in in academia.
Parenting tip #72514: keep a pair nail clippers within arms reach at all times so that, should your child happen to sit still for even a split second, you can finally get that god damned toenail.
gget alphafold: Predict the 3D structure of a protein from its amino acid sequence using @DeepMindโs AlphaFold v2.0 from a Python or command-line environment in 3 lines of code. Runs on any laptop and requires only ~4 GB of disk space. Simply โpip install ggetโ and:
@jacanamama@AmyDWillis Sweet! Looking forward to seeing the work whenever it makes it live. Would be keen to see exon sequence level vs tx expr changes!
@jacanamama@AmyDWillis Oh fascinating! so this is an interspecies comparison? Allometry controls? Wondering whether it's possible to extract signal across replicates where coverage isn't confounded with species identity. Even with heavy bias if the relevant comparison is btwn spp then probs ok!!
Just a reminder that 77 years ago my government felt that it was their best and only choice to vaporize >100k civilians to achieve their aims. And then they did it again 3 days later. I can't imagine the grief felt by survivors and those opposed to this brazenly inhumane tactic.