PJ Spencer

Mayo Rochester Cardiovascular Surgery. MCS, heart and lung transplant. MGH and Duke Trained.

[PJ Spencer @PJSpen1982]

@georgetolisjr Oh my goodness Gladwell. This is a terrible example.

[PJ Spencer @PJSpen1982]

@DrNeilStone That’s truly incredible.

[Mayo Clinic @MayoClinic]

An investigational vaccine helped the immune system recognize and respond to mutations that drive most pancreatic cancers, according to results from a clinical trial led by Mayo Clinic researchers.

Nearly every patient evaluated after receiving the vaccine developed an immune response against mutated KRAS, a gene that plays a major role in pancreatic cancer.

Learn more: https://t.co/HWBhWmeaAT

[PJ Spencer @PJSpen1982]

@KottonNelson Do you think it’s more or less effective though Dr Cotton? MRNA vs recombinant?

[PJ Spencer @PJSpen1982]

@rbarbosa91 We still
Use them on pretty much every patient in cardiac surgery. Love them, can’t top the info

[PJ Spencer @PJSpen1982]

@MiltonFriedmanW @HeartOTXHeartMD Wow

[PJ Spencer @PJSpen1982]

@HerbalistChief Children are the healthiest they’ve been in history, in the part of the world with access to vaccines and antibiotics.

[PJ Spencer @PJSpen1982]

@JSawallaGusehMD Nice Sawalla!

[PJ Spencer @PJSpen1982]

@anish_koka @georgetolisjr The OG, GT

[PJ Spencer @PJSpen1982]

@JA_RobiMD @ebender001 Is this real? Is SESATS back?

[PJ Spencer @PJSpen1982]

@georgetolisjr Oh good point.

[PJ Spencer @PJSpen1982]

@DrNeilStone Massive modern accomplishment. Another is the cure of Hep C in the 2010s.

[PJ Spencer @PJSpen1982]

@Allison_Dupont @georgetolisjr If you choose the multivalve pathway the pt will go through procedure-restenosis-procedure-restenosis etc. all evidence demonstrates you you pay for this in years of survival

[PJ Spencer @PJSpen1982]

@georgetolisjr Definitely becoming more and more common since you showed me my first TAVR explant 8 years ago. How many of these require a root replacement in your experience? > 50/50 in my experience depending on time since TAVR and diagnosis (endocarditis vs structural)

[PJ Spencer @PJSpen1982]

@Allison_Dupont @georgetolisjr I would choose a good mechanical valve first go around for myself. Somewhere between 65-75 years of I would consider a biological valve.

[PJ Spencer @PJSpen1982]

@DrDiGiorgio More efficient for whom??…

[PJ Spencer @PJSpen1982]

@SinaDaneshMD @MayoClinicCVS @PaulTangMD @Arghami @HSchaffMD @STS_CTsurgery Fantastic!

[Muath Bishawi @MuathBishawi]

Another terrific #mechsummit2026 @AATSHQ with engaging discussions, lots of learning and catching up @EmoryThoracic @EmoryCTSurgery @EmorySurgery

[PJ Spencer @PJSpen1982]

@MuathBishawi @AATSHQ @EmoryThoracic @EmoryCTSurgery @EmorySurgery Way to go Muath!

[Sahar A. Saddoughi, MD, PhD @SSaddoughi]

Thank you @AATSHQ for a successful #MechSummit2026! Grateful for the engaging discussion and collaboration across the field. I leave these meetings energized, inspired, and excited about what’s ahead in transplantation 🫁