Palesa - Calling for the end of Corruption

Interested in Politics, factors which impact on SA Economy No DMs about CRYPTOCURRENCY including Bitcoin *Watch out for Scammers they live amongst us*

[Palesa - Calling for the end of Corruption @PSeretlo]

@pule_jones @Abramjee Ensure

[Palesa - Calling for the end of Corruption @PSeretlo]

@pule_jones @Abramjee SAPS must keep tabs on her to make sure she doesn't skip the country

[Palesa - Calling for the end of Corruption @PSeretlo]

@MakhaulaT @eNCA Weren't they all acting in unison?

[Palesa - Calling for the end of Corruption @PSeretlo]

@TheRealClementM She must go but only after completing her testimony at Madlanga commission. She must still face criminal charges for malicious prosecution of Brig. Mokwele, General Khumalo and others

[Palesa - Calling for the end of Corruption @PSeretlo]

@mokone_eddie @D_Molatoli Qualification and experience is not make sure. Thank you General Mkhwanazi. Instead
Investigator Padyachee must have himself arrested together with the two others at Idac. They must leave General Khumalo, Brigadier Mokwele and their colleagues alone

[Palesa - Calling for the end of Corruption @PSeretlo]

@ZANewsFlash Enroute to which country or an arrival at CTN international airport?

[Afshine Emrani MD FACC @afshineemrani]

I'm a cardiologist. I've held dying hearts in my hands in the cath lab at 3 AM. And I need to tell you something that changes everything about how we prevent heart attacks.

For decades, the entire field was built on one target: lower LDL cholesterol. Statins save lives — that's settled science. But too many of my patients did everything right — took their statins, hit their numbers, lived clean — and still ended up on my table with a ruptured artery.

We were treating the smoke while the fire kept burning.
The fire is inflammation. And the evidence is now overwhelming.

The CANTOS trial proved it first — lowering inflammation independent of cholesterol reduced cardiac events. But the newer data is what keeps me up at night.

AI-enhanced CT angiography can now detect inflamed arteries by measuring changes in the fat surrounding your coronary vessels — the perivascular fat attenuation index. Higher inflammation in the fat around even one artery independently predicts cardiac death. When multiple arteries show inflammation, the risk multiplies dramatically — even in patients whose cholesterol looks perfect.

This isn't theoretical. This is measurable. Right now. On a scan you can get this month.

Low-dose colchicine — a drug that's been around for centuries for gout — is now FDA-approved specifically for reducing cardiovascular events. It works by quieting the inflammatory cascade that destabilizes the plaque sitting in your arteries. A pill that costs pennies is saving lives the statins couldn't reach.

And the next wave is already in Phase 3 trials. Ziltivekimab — an IL-6 inhibitor — targets the central inflammatory pathway driving atherosclerosis. Phase 2 data showed a 90% reduction in hsCRP. The ZEUS cardiovascular outcomes trial is enrolling now, with results expected late 2026 into 2027. If positive, anti-inflammatory therapy will become standard in managing heart disease alongside lipid-lowering. The era of inflammation-targeted cardiology is arriving.
But it goes deeper than drugs. AI is now predicting heart failure and cardiac events 5+ years before symptoms — integrating CT imaging, electronic health records, and genetic data with accuracy that jumps far beyond traditional risk calculators.

And polygenic risk scores — a simple genetic test that flags inherited cardiovascular risk — are now formally recognized as a risk-enhancing factor in the 2026 ACC/AHA guidelines. A single blood draw can reveal risk that's been silently building since birth. Decades before the first chest pain.

Here's what this means for you right now — today:
Ask your doctor for a high-sensitivity CRP test. It's cheap, routine, and measures the systemic inflammation that standard cholesterol panels completely miss. You can have perfect LDL and inflamed arteries that are quietly preparing to rupture.
If your hsCRP is elevated, discuss low-dose colchicine with your physician. It's FDA-approved for exactly this.
Push for a coronary CT angiography with AI plaque and inflammation analysis if you have risk factors. This isn't the stress test your parents got. This is 3D visualization of your actual arteries — with AI quantifying not just how much plaque you have, but what kind it is and whether the surrounding tissue is inflamed.
Consider polygenic risk score testing — especially with a family history of early heart disease. It's now guideline-supported.

And the foundation that never changes: move daily, eat real food, sleep 7-9 hours, manage stress, and know your numbers — ApoB, Lp(a), hsCRP, fasting insulin.
I left Iran as a child with nothing. I rebuilt everything in a country that gave me the freedom to become a physician. I've spent twenty years watching patients get second chances.

The ones who haunt me aren't the ones who died on my table. They're the ones who survived but never acted on what the science was telling them — years before the event that didn't have to happen.

You can have perfect cholesterol and still have a heart attack. Inflammation plus genetics can drive plaque rupture in arteries that look "fine" on a standard panel.
The myth that normal cholesterol means you're safe has cost more lives than I can count.

We now have the tools to detect the fire — not just the smoke. AI to see it. Genetics to predict it. Drugs to quiet it. And the ancient basics — movement, real food, sleep, purpose — to prevent it from starting.

Prevention is the new cure. And the science to make it real is no longer coming.
It's here.

[The Associated Press @AP]

Growing numbers of job applicants are no longer facing a human person in their first interview. Instead, candidates are confronted with AI chatbots designed to screen applications and assess answers before involving a human recruiter.

[Bloomberg @business]

Bank of England Governor Andrew Bailey warned the UK economy faces a worrying combination of an aging population and rapidly rising levels of young people out of work and education https://t.co/UDgxwFuFqe

[Palesa - Calling for the end of Corruption @PSeretlo]

@Sunflowerreal Closed down

[Palesa - Calling for the end of Corruption @PSeretlo]

@Sunflowerreal I remember that lady. She owned the Fourways Leaping Frog Pharmacy (Link or other franchise). It closed around a decade ago, was located opposite the Post Office, both next to Checkers, the latter closed about five years ago. The shopping centre has undergone major renovations

[Yusuf Abramjee @Abramjee]

Mkhwanazi to be Honoured as South Africa’s 2025 Newsmaker of the Year:

KwaZulu-Natal Police Commissioner Lieutenant General, Nhlanhla Mkhwanazi, will be honoured as the National Press Club’s 2025 Newsmaker of the Year at a gala event in Pretoria tonight.

The award recognises individuals who have had a significant impact on South Africa’s news agenda and public discourse over the past year.

Mkhwanazi has remained in the national spotlight through his leadership in the fight against organised crime and high-profile policing operations.

@npclub @pule_jones @HeidiGiokos @AthlendaM @SAPoliceService @DasenThathiah

[Palesa - Calling for the end of Corruption @PSeretlo]

@politicaleconZA Your argument is a non-starter, considering that your issue was in the main him working for Anglo, his role is secondary. Many SAns have worked for that company, is it a sin? SAns have had to seek employment in the corporate world to earn livelihoods to support families

[Manikivana @Manikipi]

@EFFSouthAfrica @Sinawo_Thambo A convicted offender who continues to attack the judiciary is not fit and proper to determine fitness of its functionaries.
We know this from the Hlophe judgement & NA's duty to protect its independence & integrity (s165 of the Constitution).

CIC must send fit people like qha

[Gcobani Ndzongana @gndzongana]

Lieutenant General Mkhwanazi is a strategist. He and the PKTT waited for Mother's Day, knowing it is a day when gifts and precious metals might be lying around. Give this gentleman a chance, he knows his work.

[What Happened To Sandile Kakana @truthforHank]

On 12 February 2026, Sandile Kakana was brutally murdered in his own home. 7 weeks later and there are still no answers. Sandile’s life mattered. Silence cannot be the end.
#WhatHappenedToSandileKakana

[Palesa - Calling for the end of Corruption @PSeretlo]

@unknown368290 You aren't a lateral thinker for you everything is either black or white, no grey area. I can imagine how you must have battled academically, if you can't even accept that there's a possibility of different interpretations for the same thing. Youre too simple minded to argue with

[Palesa - Calling for the end of Corruption @PSeretlo]

@unknown368290 If I was senile you wouldn't have resorted to insults, you are just too low, gone to gutter where you belong. You aren't able to engage with facts. Thanks God I have built a legacy which I don't have to prove to a faceless coward like you. You are nothing but lowlife scum

[Palesa - Calling for the end of Corruption @PSeretlo]

@unknown368290 Arrogance? Self projection I guess. Let's just agree you don't have the capacity to comprehend my assertion. At my age I've seen it all. As for you just know that birth, life, aging and death are a certainty for all of us, pray hard you reach my age and surpass it