Chi na-eme

PhD Candidate: 3D protein structures. Tweets are personal views. Now that you're here, a reminder to care for your mental health

[New York Structural Biology Center @NYSBC_Science]

Our last monthly webinar this year will be given by @Vecchiology from @Jacobs_Med_UB. To register please go to: https://t.co/lORFn91SQW
In the CryoEM current practices webinar, our users share tips and tricks that help you in your CryoEm journey.

[Alex J. Vecchio @Vecchiology]

🗣️New results from the lab fresh off the virtual press @biorxivpreprint — Biophysical Basis of Paracellular Barrier Modulation by a Pan-Claudin-Binding Molecule
🧵
https://t.co/NKUF2mwBqs

[Alex J. Vecchio @Vecchiology]

🗣️New work from the lab provides structures of the full Clostridium perfringens enterotoxin (CpE) bound to its human receptor claudin-4

https://t.co/YcXY1e5yLm

[Membrane Protein PDB @MemProtPDB]

Cryo-EM Structures of Clostridium perfringens Enterotoxin Bound to its Human Receptor, Claudin-4 | bioRxiv

https://t.co/q0h9i43nKK

[Alex J. Vecchio @Vecchiology]

New work from the lab:

🔶Cryo-EM Structures of Clostridium perfringens Enterotoxin Bound to its Human Receptor, Claudin-4🔸

https://t.co/He614t5omh

[Martin Pacesa @MartinPacesa]

Today in @Nature we present the results of our exploration of the soluble protein universe and the design of functional soluble membrane proteins with @CasperGoverde @GoldbachNico @befcorreia 1/6

https://t.co/Dakeh8Hyw7

[Martin Pacesa @MartinPacesa]

We demonstrate that using constrained design we are able to preserve functional epitopes in these analogues, such as antibody or toxin binding sites, for example for human claudins 1 and 4 - important cancer drug targets. 4/6

[Alex J. Vecchio @Vecchiology]

Now published @CommsBio “Structural and biophysical insights into targeting of claudin-4 by a synthetic antibody fragment”.

https://t.co/4vIuq2gri4 🧵

[John Innes Centre @JohnInnesCentre]

EVENT - CCP4-BCA Protein Crystallography Summer School 2024

Applications are now open for the upcoming, exciting CCP4-BCA Protein Crystallography Summer School 2024, hosted at the John Innes Centre

🗓️ Deadline - 10 June 2024

Apply and find out more: https://t.co/NqPAJ1xKDF

[Alex J. Vecchio @Vecchiology]

Go see Chi at #BPS2024.

[Chi na-eme @P_Chinemerem]

If you’re at #BPS2024 come check out my poster tomorrow at the Exhibit Hall AB, or say hi 😊

#bps #BIBPS #blackinbiophysics

[emmottlab @emmottlab]

The lab is hiring PhD students and PDRAs for 2024 start! Projects going in proteomics/mass spectrometry and virology.

[Pablo GUARDADO-CALVO @Guardado_Calvo]

A two-year postdoctoral position is available in my group at the Institut Pasteur in Paris. If you (or someone you know) are interested in viruses and/or structural biology, you can find more details below. Please retweet it :)
https://t.co/Aj6kVQdIzG

[Chi na-eme @P_Chinemerem]

@Mz_tirzah Congratulations 🎉🍾

[Chi na-eme @P_Chinemerem]

Thanks to @Vecchiology and @kapoorsrajan for making this work come to life.

[Chi na-eme @P_Chinemerem]

Check out our newest paper in the @Vecchiology lab here: https://t.co/b1mQ88x5IN.
We used both SAXS and x ray crystallography to provide a novel insight into the first step in Clostridium perfringens enterotoxin activation, oligomerization and cytotoxicity.

[Adam Mustapha, PhD., FASLN. @DrAdmusty]

Come and do PhD with us. We have interesting research areas, and Erudites and amazing Faculty members and researchers.

[Chi na-eme @P_Chinemerem]

@CrystalUminski Congratulations Dr. Uminski 🥳🥳🍾🍾

[Alex J. Vecchio @Vecchiology]

In this new preprint we used cryo-EM and a novel Fab to determine a 2.6 Å structure of 22 kDa claudin-4 bound to a 14 kDa bacterial enterotoxin domain.

https://t.co/dFWR7v0arh

[Tofayel Ahmed @tofayel_ahmed1]

Cryo-EM PhD position available in my lab starting from August 2023!