Consultant Paediatric Surgeon at Great Ormond Street Hospital/UCL Institute of Child Health with interest in congenital malformation and regenerative medicine
Our latest study, just published in @TheLancet, reports the first successful transition from porcine kidney #xenotransplantation to human kidney transplantation.
A genetically engineered pig kidney provided >9 months (271 days) of dialysis-free kidney function before successful human transplantation, supporting xenotransplantation as a potential bridge while preserving future transplant options.
Beyond the clinical milestone, the study provides new insights into late microvascular inflammation and innate immune activation that will help shape future immunosuppressive strategies and donor genetic engineering.
Link to article: https://t.co/RCZFq2w5vD
@mgh_transplant@MGHSurgery@MGBResearchNews@MGBKidneys@eGenesisBio
We have shown that lab-grown oesophagus successfully replaces a full segment and restores swallowing without immunosuppression. https://t.co/TMmXq1qhYM
A major step forward for children with long-gap oesophageal atresia. @GOSHCharity@UCLPopHealthSci@ucl@NEWSFORTOFS
An international research team led by UCL, Great Ormond Street Hospital, and KU Leuven is using 3D-printing and nanodiamonds to design treatments that could help babies repair their damaged lungs while still in the womb.
https://t.co/KTYSSySwWQ
Very impressive JPS Lecture by @augusto_zani at BAPS. He has done tremendous work in Toronto and now in St Louis. Very lucky to have him as friend and collaborator
Preterm & sick #neonates need better care to improve survival & long-term health. More investment & commitment in #neonatology can help developing more research and development to advance high-quality care for all #newborns@EupsaSurgeons https://t.co/DqDdKc3RVH
Delighted to share update prospective on @natrevbioeng regarding organ engineering using decellularized tissue scaffolds. Thanks to
@GiobbeGiovanni Lorenzo Caciolli, Tarek Saleh @GreatOrmondSt@UCLchildhealth https://t.co/7wGmVnxlkU
@EUPSA in Dubrovnik 🇭🇷
As my term as President ends, I’m deeply grateful for the trust, support & collaboration. It’s been an honour to serve this amazing community of paediatric surgeons. Here's to EUPSA’s continued growth & impact! 👏