Passalab

A young team at the University of Milan having fun with organic synthesis and medicinal chemistry!

[Passalab @Passa_lab]

We are thrilled to announce our latest publication in Nature Communications, detailing the rational drug discovery of new candidates aimed at restoring physiological microtubule interactions. You can have a look at:
https://t.co/2fTqJa2Rn3
@LaStatale

[EurJOC @EurJOC]

A Green Approach to Nucleophilic Aromatic Substitutions of Nicotinic Esters in Cyrene by Andrea Citarella, Valerio Fasano, and co-workers (@valeriofasano @Passa_lab @LaStatale) https://t.co/U0UURxi1zw

[Passalab @Passa_lab]

Our group exploits the chemistry of boronic acids to access novel functionalized scaffolds!

[Passalab @Passa_lab]

We also work on the treatment of neurodegenerative diseases such as retromer stabilization!

[Passalab @Passa_lab]

Our group is interested in the development of more efficient methods for the synthesis and functionalization of heterocycles!

[Passalab @Passa_lab]

Our research also focuses on the development of novel PROTACs!

[Passalab @Passa_lab]

In the last couple of years, we have developed novel SARS-CoV-2 Mpro Inhibitors with Anticoronavirus Activity!

[Passalab @Passa_lab]

The total synthesis of natural products, especially cannabinoids, is at the heart of our research!

[Passalab @Passa_lab]

A project our group is interested in is the synthesis of self-assembled nannoparticles and conjugates for drug delivery!