Patrycia Z

Following radical cyclizations through photochemical methods :^)

[Patrycia Z @PatKZy]

Use of photochemistry to promote isomerization and transannular cyclization for heterocycles with enone/dienone functionalities.
@chem433 #chemtwitter
https://t.co/9P0iT0NlaH

[Patrycia Z @PatKZy]

Interesting paper on "XAT" (Halogen-Atom Transfer) applications, specifically in radical cyclizations and the total synthesis of (±)-hirsutene. @chem433 #chemtwitter
https://t.co/fBisR5lv8R

[Patrycia Z @PatKZy]

Good read on the fundamentals of solvent choice and how it modifies the energies between electronic states in photochemical reactions!
@chem433 #chemtwitter

https://t.co/CztB7likXG

[Patrycia Z @PatKZy]

Light-promoted radical addition and 1,5-HAT cyclization process for synthesizing tetralone cores, a skeleton present in many biologically active molecules.

@chem433 #chemtwitter

https://t.co/RVnZ3zO8Ga

[Patrycia Z @PatKZy]

A unique and photochemically enabled hydroaminoalkylation (HAA) reaction for complex alkylamine synthesis. @chem433 #chemtwitter

https://t.co/743rs5iFzM

[Patrycia Z @PatKZy]

Useful synthesis of a currently unexplored building block in drug design!
@chem433
#chemtwitter https://t.co/i1A81LbHOE

[Patrycia Z @PatKZy]

Interesting article on amide activation towards radical cyclization using photochemistry and fluorine.
@chem433 #chemtwitter

https://t.co/BkaiCAuXYh

[Patrycia Z @PatKZy]

Interesting paper reporting novel photochemical rearrangements of N-cyclopropylimines to 1-pyrrolines, a common ring system found in natural products! @chem433 #chemtwitter

https://t.co/xN1U0sxwgt

[Patrycia Z @PatKZy]

https://t.co/ryiDwydhL4
@chem433 #ChemTwitter

[Patrycia Z @PatKZy]

Cool way of selectively synthesizing cyclopropanes through photochemical methods. Particularly of interest is how they avoided competitive C-H functionalization by using cyclooctatetraene, an underused synthetic substrate that undergoes a "tub" conformation to stay aromatic.