Are you concern a possible lymphoma?Keep the specimen fresh (donβt place it in formalin) and communicate with your pathology team. We will take care of the rest π @PathPearls@PATHtweets
Why should we send the specimens from the OR to the Lab ASAP? Autolysis starts as soon as tissue is removed from the body! Delaying formalin fixation can result in failure (false negatives) of tumor markers in the tissue, altering the type of therapy (and outcome) for the patient
See below β¬οΈ HER2, ER and PR markers can be falsely negative due to delay in fixation. Accurate determination of biomarkers is essential for the proper management of breast cancer patients @pathpearls
@MirunaPopescu13 Correct! It is highly variable around the world π. In some countries you can only do Anatomic Pathology and the clinical labs are completely separate.
Did you know that pathology residency lasts 3-4 years? Pathologist in training can choose to study anatomic or clinical pathology. Studying one=3 years, studying both (AP/CP) = 4 years!
Should I include clinical history in the pathology request form? π¬ Yes, please! Knowing more about the clinical history of this patient or the indications for sending a sample to path is very helpful to correlate the histologic findings in the right context π€ #pathpearls
Our goal is to clear up some of the misconceptions about pathology and help bridge the communication gap between pathologists and physicians. Letβs start! π¬