Penn CREST

Center for Real World Effectiveness and Safety of Therapeutics @Penn Director:@HennessySean

Follow Us @

[Penn CREST @Penn_CREST]

We are moving this account to BlueSky. Please give us a follow @ https://t.co/5YHPrgPI9A !

https://t.co/KaXVuaJKnn

[Penn CREST @Penn_CREST]

Great new paper in ACR Open Rheumatology, led by CREST investigator Josh Baker:

Characterization of Second-Line Therapy After First JAK Inhibitor Use: Results From the CorEvitas Rheumatoid Arthritis Registry

@UPennDBEI
https://t.co/RSdkgqI2RT

[Penn CREST @Penn_CREST]

New in JAMA Health Forum:

Stimulant Overdose Prediction Model for Medicaid-Insured Persons

@UPennDBEI @HennessySean

https://t.co/2DveuPtl5m

[Penn CREST @Penn_CREST]

New in American Journal of Epidemiology:

Effect of exogenous testosterone on cardiovascular, cerebrovascular, and thromboembolic adverse events: Results of three complementary research designs
@TatThangVo1 @phuongpng @HennessySean @CE_Leonard

https://t.co/zDN6c2pt3L

[Penn CREST @Penn_CREST]

New in Pharmacoepidemiology & Drug Safety ⬇️

Real-World Data and Real-World Evidence in Regulatory Decision Making: Report Summary From the Council for International Organizations of Medical Sciences (CIOMS) Working Group XIII

@HennessySean @UPennDBEI

https://t.co/oDEHp4YCMi

[Penn CREST @Penn_CREST]

Great new paper in Clinical Pharmacology & Therapeutics led by doctoral student Haedi Thelen:

Characterizing Treatment Effect Heterogeneity
Using Real-World Data

https://t.co/RyWp9mNAHv

@HaediThelen @HennessySean

[Penn CREST @Penn_CREST]

Check out the latest from the CREST team in Pharmacoepidemiology & Drug Safety:

Evaluation of Drug–Drug Interactions in Pharmacoepidemiologic Research
@Alicechencheng @phuongpng @Miano81 @CE_Leonard @HennessySean

https://t.co/4XLVoHrJh2

[Penn CREST @Penn_CREST]

New publication in Journal of Geriatric Psychiatry and Neurology led by @phuongpng and featuring several CREST investigators ⬇️

Impact of Anticholinergic Burden and Clinical-Demographic Characteristics on Incident Dementia in Parkinson Disease

https://t.co/Wib6f4BHZo

[Penn CREST @Penn_CREST]

A great methods paper featuring several CREST investigators, newly published in the Electronic Journal of Statistics:

Structural mean models for instrumented difference-in-differences

@TatThangVo1 @HennessySean @UPennDBEI

https://t.co/u6pT1a8KuB

[Penn CREST @Penn_CREST]

Newly published in Clinical Pharmacology and Therapeutics and featuring several CREST investigators:

Risk of Hypoglycemia Associated with Concomitant Use of Insulin Secretagogues and ACE Inhibitors in Adults with Type 2 Diabetes: A Systematic Review

https://t.co/XtUCZD6e93

[Penn Medicine CSO @PennMedCSO]

Ambient temperature & serious adverse health outcomes among users of different antidiabetes drugs ft. @CE_Leonard, Kacie Bogar, Colleen Brensinger, Warren Bilker, @Alicechencheng & @HennessySean @Penn_CREST @UPenn_CCEB @UPennDBEI @PennSysPharmATT
https://t.co/3WGhsKZp3n

[Penn CREST @Penn_CREST]

Interested in joining the CREST team? We're hiring! ⬇️

Manager Research Project B (Department of Biostatistics, Epidemiology and Informatics)

https://t.co/4JVPcG9Kfs

[Penn CREST @Penn_CREST]

Check out the latest in JAMA Network Open, led by CREST investigator Mark Neuman ⬇️

Strategies to Limit Benzodiazepine Use in Anesthesia for Older Adults: A Randomized Clinical Trial
@neumanmd

https://t.co/iF1oodDaGO

[Penn CREST @Penn_CREST]

Spotlighting an excellent paper by one of our first-year PhD students, Lin-Chieh Meng!

Paternal metformin use and risk of congenital malformations in offspring in Norway and Taiwan: population based, cross national cohort study
@LinChiehMeng

https://t.co/gkW46HR1mn

[Penn CREST @Penn_CREST]

Newly published in Clinical Pharmacology & Therapeutics ⬇️

Risk of Opioid Overdose Associated with Concomitant Use of Methadone and Statins
@Alicechencheng @Miano81 @CE_Leonard @HennessySean

https://t.co/vDO1DvblSO

[Penn CREST @Penn_CREST]

Check out the latest from the CREST team in Clinical Pharmacology & Therapeutics ⬇️

Concomitant Use of Oral Anticoagulants with Oral Dipeptidyl Peptidase-4 Inhibitors and Serious Bleeding Events
@phuongpng @HennessySean @CE_Leonard @Miano81

https://t.co/sTjXyA6TU2

[Penn CREST @Penn_CREST]

A great first day of sessions at #ISPEAnnual2024 in beautiful Berlin!

[Penn CREST @Penn_CREST]

New in the American Journal of Epidemiology and led by our talented former post doc Hanxi (Molly) Zhang) ⬇️

Grace periods and exposure misclassification in self-controlled case-series studies of drug-drug interactions
@CE_Leonard @HennessySean @Miano81

https://t.co/zwZwxzRYE0

[Penn CREST @Penn_CREST]

Newly published in JAMA Neuro. and led by our own Emily Acton ⬇️

Direct-Acting Oral Anticoagulants and Antiseizure Medications for Atrial Fibrillation and Epilepsy and Risk of Thromboembolic Events
@HennessySean @CE_Leonard @UPennDBEI

https://t.co/bs4FIOz7O4

[Penn CREST @Penn_CREST]

Check out the latest in JAMA Internal Medicine featuring several CREST investigators ⬇️

Severe Acute Liver Injury After Hepatotoxic Medication Initiation in Real-World Data
@HennessySean @UPennDBEI

https://t.co/O9hyFVkwHC