Thrilled to have worked on this project with such an amazing and adaptive team! Congrats to all, especially @aquino_yann @MonsieurRoti @QuintanaMurci for seeing this across the finish line!
Our collaborative effort on the ever-sneaky C difficile, which has been spreading globally for the past few decades with cryptic DR https://t.co/Hnszc4ntHJ
Join us on Wednesday (7/19) at 10:00AM in 1120 Biochemistry for an exciting #MDTP dissertation defense seminar! Madison Youngbloom from Dr. Pepperell's lab will present her work on "Identifying signatures of bacterial adaptation to pathogenic niche using evolutionary genomics"
@ppgardne@ZaminIqbal I mean I wouldn't expect the trait to be phylogenetically clustered. Inferring competence in silico would mean disentangling from all the other mechanisms of HGT. Something we attempted in the paper I linked.
@ZaminIqbal Here [10.1093/gbe/evu175] we used patterns of HGT to hypothesize underlying mechanism. Extending this in silico approach might help to define a less biased classification of competent bacteria [w/ many caveats]