Caitlin Pepperell

@[email protected]
ID doc and researcher on population genetics, ecology and evolution of infectious diseases affecting humans.

[Akos T. Kovacs @EvolvedBiofilm]

Adaptation of the Mycobacterium tuberculosistranscriptome to biofilm growth

@PLOSPathogens from @Pepperell_Lab

https://t.co/pSnANPq5KG

[UW-Madison Division of Infectious Disease @uw_infdisease]

📍 Meet our amazing APP Lead @MeghannID_DNP! Meghann works with our general ID service. 🩺

[M.B. O'Neill @ONeillMB1]

Thrilled to have worked on this project with such an amazing and adaptive team! Congrats to all, especially @aquino_yann @MonsieurRoti @QuintanaMurci for seeing this across the finish line!

[Caitlin Pepperell @Pepperell_Lab]

Wonderfully clear talk from @CreanzaLab on bird song evolution at #SMBE2023 bonus points for bird-themed garb

[Alex Cagan @ATJCagan]

Nicole Creanza on the interactions between socially learned song and speciation in songbirds #smbe23 #smbe2023 using data from @Team_eBird

[Caitlin Pepperell @Pepperell_Lab]

@ZaminIqbal See you there :)

[Caitlin Pepperell @Pepperell_Lab]

Our collaborative effort on the ever-sneaky C difficile, which has been spreading globally for the past few decades with cryptic DR https://t.co/Hnszc4ntHJ

[Microbiology Doctoral Training Program @UWMadisonMDTP]

Join us on Wednesday (7/19) at 10:00AM in 1120 Biochemistry for an exciting #MDTP dissertation defense seminar! Madison Youngbloom from Dr. Pepperell's lab will present her work on "Identifying signatures of bacterial adaptation to pathogenic niche using evolutionary genomics"

[Caitlin Pepperell @Pepperell_Lab]

Also interestingly, sub-populations encoding the element appear to inhabit slightly distinct niches, reflected in patterns of HGT

[Caitlin Pepperell @Pepperell_Lab]

The latest from the lab: https://t.co/ehKKjVbH4j

[Caitlin Pepperell @Pepperell_Lab]

There is evidence of co-adaptation between element and the core genome, particularly a previously uncharacterized gene with fascinating proclivities

[Caitlin Pepperell @Pepperell_Lab]

@docfreeride Plant + grow light + self watering pot

[Caitlin Pepperell @Pepperell_Lab]

@ppgardne @ZaminIqbal I mean I wouldn't expect the trait to be phylogenetically clustered. Inferring competence in silico would mean disentangling from all the other mechanisms of HGT. Something we attempted in the paper I linked.

[Caitlin Pepperell @Pepperell_Lab]

@ZaminIqbal Here [10.1093/gbe/evu175] we used patterns of HGT to hypothesize underlying mechanism. Extending this in silico approach might help to define a less biased classification of competent bacteria [w/ many caveats]

[Caitlin Pepperell @Pepperell_Lab]

@ZaminIqbal And conditions easily replicated in the lab, with a heavy dose of serendipity.

[Caitlin Pepperell @Pepperell_Lab]

@vscooper Yes, yes you can