Vlad

[Massimo @Rainmaker1973]

A man with diabetes is making his own insulin after cell transplant.

A 42-year-old man with type 1 diabetes has become the first patient in the world to naturally produce insulin again after receiving gene-edited pancreatic cells.

Using CRISPR-Cas12b technology, scientists reprogrammed donor islet cells to evade immune system attacks that normally destroy transplanted tissue in diabetics. This breakthrough eliminates the need for lifelong immunosuppressive drugs, which often carry severe side effects.

The patient received nearly 80 million of these “hypoimmune” cells, which survived and thrived in his body. Four months later, doctors confirmed the cells were producing insulin by detecting C-peptide spikes after meals.

While still in early trials, this marks a potential revolution in diabetes care, showing that the disease could one day be managed without daily insulin injections. If scaled, it could transform the lives of millions living with type 1 diabetes worldwide.

[Carlsson, Per-Ola, et al. “Survival of Transplanted Allogeneic Beta Cells with No Immunosuppression.” The New England Journal of Medicine, Aug. 4, 2025.]

[Garry Kasparov @Kasparov63]

Yes, and I raged about Obama mocking him for it. But just a few years later, Republicans embraced enemy Russia because of Trump's loyalty to Putin and began the "Russia hoax" gaslighting that still persists. There’s being wrong and there’s being a traitor.

[ian bremmer @ianbremmer]

middle of a war during a naval blockade is an interesting moment to dump your naval secretary.

[Vlad @Pilich]

@SkinInTheGme Not verified, but I get your updates.

[Gary Koepnick @garykoepnick]

Just going to keep posting this to counter the ridiculous bullshit until someone makes me stop.

The Special Counsel investigation uncovered extensive criminal activity
•The investigation produced 37 indictments; seven guilty pleas or convictions; and compelling evidence that the president obstructed justice on multiple occasions. Mueller also uncovered and referred 14 criminal matters to other components of the Department of Justice.
•Trump associates repeatedly lied to investigators about their contacts with Russians, and President Trump refused to answer questions about his efforts to impede federal proceedings and influence the testimony of witnesses.
•A statement signed by over 1,000 former federal prosecutors concluded that if any other American engaged in the same efforts to impede federal proceedings the way Trump did, they would likely be indicted for multiple charges of obstruction of justice.

Russia engaged in extensive attacks on the U.S. election system in 2016
•Russian interference in the 2016 election was “sweeping and systemic.”[1]
•Major attack avenues included a social media “information warfare” campaign that “favored” candidate Trump[2] and the hacking of Clinton campaign-related databases and release of stolen materials through Russian-created entities and Wikileaks.[3]
•Russia also targeted databases in many states related to administering elections gaining access to information for millions of registered voters.[4]

The investigation “identified numerous links between the Russian government and the Trump Campaign” and established that the Trump Campaign “showed interest in WikiLeaks's releases of documents and welcomed their potential to damage candidate Clinton” 
•In 2015 and 2016, Michael Cohen pursued a hotel/residence project in Moscow on behalf of Trump while he was campaigning for President.[5]Then-candidate Trump personally signed a letter of intent.
•Senior members of the Trump campaign, including Paul Manafort, Donald Trump, Jr., and Jared Kushner took a June 9, 2016, meeting with Russian nationals at Trump Tower, New York, after outreach from an intermediary informed Trump, Jr., that the Russians had derogatory information on Clinton that was “part of Russia and its government’s support for Mr. Trump.”[6]
•Beginning in June 2016, a Trump associate “forecast to senior [Trump] Campaign officials that WikiLeaks would release information damaging to candidate Clinton.”[7] A section of the Report that remains heavily redacted suggests that Roger Stone was this associate and that he had significant contacts with the campaign about Wikileaks.[8]
•The Report described multiple occasions where Trump associates lied to investigators about Trump associate contacts with Russia. Trump associates George Papadopoulos, Rick Gates, Michael Flynn, and Michael Cohen all admitted that they made false statements to federal investigators or to Congress about their contacts. In addition, Roger Stone faces trial this fall for obstruction of justice, five counts of making false statements, and one count of witness tampering.
•The Report contains no evidence that any Trump campaign official reported their contacts with Russia or WikiLeaks to U.S. law enforcement authorities during the campaign or presidential transition, despite public reports on Russian hacking starting in June 2016 and candidate Trump’s August 2016 intelligence briefing warning him that Russia was seeking to interfere in the election.
•The Report raised questions about why Trump associates and then-candidate Trump repeatedly asserted Trump had no connections to Russia.[9]

[Vlad @Pilich]

My wife’s a teacher. She’s had 31 kindergarten kids at once, some with severe complex needs and no support. She’s been bit, hit, spat at, and had to evacuate her class for safety. Teachers aren’t striking for money; they’re striking for help. https://t.co/7ksRRrpx6O

[Piers Morgan @piersmorgan]

So, Russia can illegally invade a sovereign democratic European country, murder 1000s of Ukrainian civilians, then rope in North Korean soldiers to help them wage war, and the West’s correct response should be to.. *checks notes* … give Putin what he’s stolen?
Do f*ck off.

[Elon Musk @elonmusk]

And it will improve significantly from here

[Garry Kasparov @Kasparov63]

Ukraine is fighting for the free world that is refusing to give them the weapons to win. Imagine if US or German civilians were being bombed and your govt withheld arms to defend them. That's essentially what's happening. It's unconscionable.

[Maksym Borodin @adnashmyash]

Back in 2014, John McCain fully predicted Putin's next moves.
"Not to provoke Putin is to show weakness, which will 100% provoke Putin"
"A developing and democratic Ukraine is a threat to Putin's power"
"He will try to cut more Ukraine and then Baltics"

[Garry Kasparov @Kasparov63]

Because it's so outrageous, I'm going to start at the bottom of the barrel with Tucker for this thread on Zelensky's visit to DC, the Biden admin's success and failure, and the future of American support for Ukraine and global security. 1/10

[Vlad @Pilich]

Meteor #caughtonNestCam https://t.co/uHtXddRpBo via @Nest

[Vlad @Pilich]

@elonmusk Forget the tug-o-war, I want to see which one can survive re-entry.

[Vlad @Pilich]

@elonmusk I'm a bit concerned about the huge pane of glass and rock chips. We get a lot of rock chips where I live. Could be expensive.

[Vlad @Pilich]

Discovered that the vegetable drawer is the best place to hide my chocolate, since nobody ever looks there.

[Vlad @Pilich]

@nsxdavid @Pilich Thanks, it's working for me too!

[Vlad @Pilich]

Taking care of Jason who has the stomach flu :-(