Laboratory for Precision Neuroimaging @UCSF. PI’s: @rahuldesikan, @leosugrue. We study brain disease using imaging, genetics, health, and behavioral data.
Dr. Rahul Desikan & his team at UCSF @PrecisionNeuro are building a free online genetic platform for #ALS patients to calculate genetic risk. https://t.co/fUI9whlFih
Polygenic hazard score, amyloid deposition and Alzheimer's neurodegeneration. Beyond APOE, polygenic hazard scores in living subjects were associated with amyloid deposition and neurodegeneration in susceptible brain regions. https://t.co/rtg0K69NGz @rahuldesikan@ADNI3study
'Polygenic hazard score, amyloid deposition and Alzheimer's neurodegeneration' --> New #research from the @PrecisionNeuro team. https://t.co/zcFOgV3mHj
"...these findings further suggest a nuanced relationship between polygenic risk and markers of amyloid deposition, pathological tau and neurodegeneration"
This is my own genetic data run on our tools - looks like I'd benefit from stem cells and oxidative therapies - this is the real potential for #Genomics for #ALS#treatments - we can do this and any #PALS#fightALS
Our new findings suggest that subsets of ALS patients are at elevated genetic risk for FTD, cardiovascular, or immune dysfunction. Developing multiple pathway polygenic scores in this regard would be important for informing therapies.
Welcome to the official page of the Laboratory for Precision Neuroimaging @UCSF! Led by Drs. Rahul Desikan @rahuldesikan and Leo Sugrue @LeoSugrue. Please follow us for major updates and news from the lab!
Hello! I have written an explainer on genome-wide association studies and genetic risk.
https://t.co/1bXok9qjRQ
Working on this story made me feel like my brain was going to explode.