Protein & Cell

Protein & Cell aims to present novel discoveries in biological science. A Peer Review, Global Open Access, Green Channel to Rising Stars.

[Protein & Cell @Protein_Cell]

This study systematically maps the molecular landscape of primary tumors and matched metastatic lymph nodes and reveals the molecular features, potential biomarkers, and potential molecular mechanism for lymph node metastasis.https://t.co/uVEZnZSu9j

[Protein & Cell @Protein_Cell]

A cryo-electron microscopy structure of the polar flagellar motor in complex with the hook from Vibrio alginolyticus reveals the molecular basis for high-torque transmission and the forward-reverse-flick motility pattern. https://t.co/RoWnhrfN9r

[Protein & Cell @Protein_Cell]

https://t.co/OCoJZ61IWF

[Protein & Cell @Protein_Cell]

https://t.co/icjqlVyFGx

[Protein & Cell @Protein_Cell]

https://t.co/vKxI11mEKo

[Protein & Cell @Protein_Cell]

https://t.co/mFILABzH9L

[Protein & Cell @Protein_Cell]

Protein&Cell科研能力提升营怀科城站活动先导片 https://t.co/A81FRQGVF7 via @YouTube

[Protein & Cell @Protein_Cell]

Episode 41th Protein & Cell Scholars Forum (学者讲坛) Replay by Dr. Fan Yang group from Northwest A&F University: https://t.co/mgF1iD2HlF

[Protein & Cell @Protein_Cell]

Our Rising Star's Camp in Insitute of Biophysics, CAS came to a happy ending! https://t.co/pcykdX7XMM

[Protein & Cell @Protein_Cell]

Protein&Cell科研能力提升营中科院生物物理所站即将开启 https://t.co/7THlYJvG9e via @YouTube

[Protein & Cell @Protein_Cell]

Episode 40th Protein & Cell Scholars Forum (学者讲坛) Replay by Dr. Yuting Guo group from University of Chinese Academy of Sciences: https://t.co/CwUUqCe3sw

[Protein & Cell @Protein_Cell]

Protein&Cell Rising Star's Camp in IBP is set to start on 23rd April!

[Protein & Cell @Protein_Cell]

Using cryo-EM and molecular dynamics simulation, this study reveals three functional states of GHRHR: the ligand-free (Apo) and the allosteric agonist PCO371-bound Gs-coupled active states, and the antagonist MIA-602-bound inactive state, illuminating ligand-specific conformational adaptation.https://t.co/PVXOwuXZwO

[Protein & Cell @Protein_Cell]

This review covers tumor organoid sources, establishment and culture systems, modeling carcinogenesis, heterogeneity, evolution and metastasis, tumor microenvironment reconstruction, clinical translation and trials and remaining challenges, standardization, ethics, and future directions.https://t.co/RYvkRsjGhq

[Protein & Cell @Protein_Cell]

This study identifies DUX-mediated phase separation as a key driver for 3D genome reorganization and super-enhancer assembly, licensing totipotency gene expression and providing mechanistic insights into early development and FSHD. https://t.co/6MCscFNAPU

[Protein & Cell @Protein_Cell]

Next-generation immune-integrated models enable dynamic, physiologically relevant platforms to study aberrant wound healing mechanisms, accelerating drug discovery and precision therapeutic development. https://t.co/QMhJkPDSqi

[Protein & Cell @Protein_Cell]

BHB exerts an inhibitory effect on colorectal cancer growth by targeting the mTORC1 pathway through β‑hydroxybutyrylation of RagC at lysine 349. https://t.co/ILrfyvLu1f

[Protein & Cell @Protein_Cell]

Episode 39th Protein & Cell Scholars Forum (学者讲坛) Replay by Dr. Jianming Li group from Sun Yat-sen University: https://t.co/abA0TP1YSI

[Protein & Cell @Protein_Cell]

Stimulation of α7 nAChRs played a role in suppressing PARP1 hyperactivation and PAR production, consequently reducing the α-syn aggregation and toxicity in Parkinson's disease.https://t.co/1rj4t25TFm

[Protein & Cell @Protein_Cell]

Sphingosine-1-phosphate receptors are the targets for treating many human diseases and selectivity is one of the major hindrances during drug development. Two crystal structures of human sphingosine-1-phosphate receptor 3 in complex with one bitopic ligand SPM-242 as well as allosteric ligands Cpd-32 or CYM52581 bound simultaneously was reported, and together with cryo-electron microscopy structures of S1P2 and S1P3 in complex with heterotrimeric Gi protein, the activation process of Sphingosine-1-phosphate receptors is revealed and the key sites for designation of better selective S1P ligands are proposed.https://t.co/uOMCe8aB9O