Xeruborbactam (formerly QPX7728) is a highly differentiated ultra-broad-spectrum beta-lactamase inhibitor in clinical studies in IV & oral forms for #AMR. Hear from one of the inventors, our head of chemistry @Scottjhecker on how to pronounce the new given name “xeruborbactam”:
Antimicrobial resistance (AMR) occurs when pathogens develop resistance to the medicines designed to treat them. It's a growing global health threat. In this @Nature supplement, Gareth Morgan explores economic solutions to drive antibiotic innovation. https://t.co/0n1mYIaZAU
#News: @BARDA has awarded Shionogi Inc. a new contract to advance our #antibiotic against biothreats and drug-resistant pathogens. Initially funded at $119M with options up to $482M, this contract also supports a new U.S. manufacturing site and procurement.
https://t.co/zAviirAoCi
#NEWS: We welcome Gareth Morgan, longstanding Shionogi team member and global leader, to Qpex as President.
Morgan succeeds @MikeMndudley , Pharm.D., who is retiring and will serve as a strategic advisor to Qpex and Shionogi.
Learn more: https://t.co/vANlqvMatH
We look forward to continuing collaboration with leaders like Dr. Jacinda Abdul-Mutakabbir, AKA Dr. JAM at our new San Diego, R&D facility.
A researcher, educator and clinician, she sees resistant infection problems from multiple POVs.
Learn more: https://t.co/GulmrO91zZ
We were honored to have Dr. Karen Bush share her perspectives at the opening of our new antimicrobial R&D facility in San Diego. Throughout her career, Dr. Bush has driven innovation through industry, government and academic collaborations.
Learn more: https://t.co/tFjWHBIBme
We recently celebrated the official opening of our expanded U.S.-based drug discovery lab in San Diego, which will support antimicrobial research and development (R&D) for decades to come.
Learn more: https://t.co/GulmrO91zZ
Welcome Lynn Connolly, MD, PhD as Chief Medical Officer. With more than 12 years of experience in developing infectious disease treatments, she will lead our clinical development programs and help drive innovation in our expanding drug discovery programs.
@Qpexbio is committed to continuing its position as a leader in innovation and development of therapies in infectious diseases. We are honored to have Michael Dudley presenting at @SIDPharm annual meeting held in conjunction with @IDWeekmtg .
At the @SIDPharm Annual Meeting, Michael Dudley, PharmD, President & CEO of @Qpexbio, a Shionogi Group Company, will deliver the keynote address. He’ll share insights from his journey in academia to industry R&D, highlighting his role in developing four key antibiotics. #SIDP2024
In July's LifeLines Newsletter, discover how Yatiri Bio uses proteomics to revolutionize cancer drug discovery, how the Shionogi lab @Qpexbio progresses antimicrobial resistance research, and how our members drive precision medicine forward. Read more: https://t.co/Psos4NQXDz
“The expertise of @ShionogiUS & @Qpexbio scientists in this facility in the U.S. will enhance drug discovery and development efforts & help make medicines available that can support future public health,economic & nat’l security concerns.”- Phyllis Arthur, Exec VP @IAmBiotech
#ICYMI: We’re establishing our first discovery laboratory in the U.S. The R&D facility for @Qpexbio, a Shionogi Group Company, will build on our longstanding legacy in infectious disease. Learn more: https://t.co/l0SpZNXVeB
#BIO2024
@Qpexbio scientists will present microbiological data and Phase 1 results for oral xeruborbactam - the first orally bioavailable beta-lactamase inhibitor with inhibitory activity against both serine and metallo beta-lactamases.
Pathogens will always stay one step ahead of available treatments and that’s why we're committed to developing new antibiotics. Together with @Qpexbio, we're presenting new data on our investigational beta-lactamase inhibitor at #ESCMIDGlobal.
Learn more about our pipeline at https://t.co/SEtUXQgM1K
#ECCMID2024
🆕 #Breakpoints Episode:
Join @hboucher3, Ramy Elshaboury, @MikeMNDudley & @MeganKlatt3 to discuss barriers to abx drug development, incentives & legislation to promote market growth, & what we can do to ensure the abx pipeline doesn’t run dry.
🎧 https://t.co/ez0n3ae0fR
Time is of the essence for patients with infections caused by carbapenem-resistant pathogens. Mortality risk increases with every hour that treatment is delayed.
Learn more about Gram-negative bacterial resistance and treatment strategies with @GoHealio: https://t.co/sxwR1cPpMw
Attending #IDWeek2023? Join Olga Lomovskaya, PhD, SVP, Discovery and Clinical Microbiology, @Qpexbio, on October 12 to hear about new antimicrobials in the pipeline. #InfectiousDiseases
Beta-lactamase inhibitors have been an important strategy for combatting #AMR. Want to finally see comparative head-to-head data on investigational & marketed beta-lactamase inhibitors? We publish results here… https://t.co/V5Y5UlqAXI
We’re delighted to announce that we’ve signed an agreement with Orchid Pharma Ltd to manufacture cefiderocol 👏
This agreement is a critical step forward in our project with @SHIONOGI_JP & @CHAI_health to improve appropriate antibiotic access
👉https://t.co/H8Ce1AArQH
#AMR due to NDM beta-lactamase continues to amaze in its evolution, including NDM-9 & resistance to some beta-lactamase inhibitors. We describe here: https://t.co/VrJ2ApHFFI