Interested in the development of brain folding? We have 2 postdoc positions to study the molecular and mechanical causes of brain folding!
Thread 1: Modelling different hypotheses of brain folding
Thread 2: Multimodal, multi-scale atlas
@BorrellLab@neuroliege@Franze_Lab (1/3)
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To predict the behaviour of a primate, would you rather base your guess on a closely related species or one with a similar brain shape? We looked at brains & behaviours of 70 species, you’ll be surprised!
🧵Thread on our new preprint with @R3RT0 , https://t.co/668msRHMNu
@BenjaminLy61243@katjaQheuer@LFeldmanBarrett The idea has deep roots! We have a chapter on the Evolution of cortical folding ready to go. We talk a bit about the Developmental Mechanics of Wilhelm His back in ~1844. I'll have to check Bernstein. Any reference in particular? (I started following you on bsky 😋)
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All this suggests that mechanical morphogenesis may be a major 3rd causal determinant of the development and evolution of brain organisation in primates.
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Zoom into illustration #2: New World monkeys like capuchins have much more folded brains than their Marmoset cousins. Surprisingly, their folding pattern is almost identical to that of Old World monkeys like macaques despite ~47my independent evolution—as much as whales&hippos!
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Lining up primate brains solely based on their size provides a 1st striking illustration of the importance of mechanical morphogenesis: despite jumping across far branches of the phylogenetic tree, the sequence is continuous, hinting at a common underlying organising principle.
Lifestyle is a stronger predictor of aging and mortality than genetics.
A new Nature study of ~500,000 people found:
🎯 17% of mortality variation was linked to lifestyle (exposome).
🧬 <2% of was explained by genetics.
Here’s what you need to know 👇🧵 1/10
@ECaruyer@JakobWasserthal Thank you @ECaruyer for the shoutout :D
We still use https://t.co/EzeD2zOBpX for all our manual segmentation needs. For example, the segmentations for @katjaQheuer's paper on the cortical folding of 34 primate species were all done using BrainBox!
https://t.co/xlKjHo8nUF
Short-range Fgf signalling patterns hindbrain progenitors to induce the neurogenesis-to-oligodendrogenesis switch
Read this #OpenAccess Research Article by Tim Yeung @tim_justina and David Wilkinson @TheCrick:
https://t.co/jD8NcwiFVW
Svante Paäbo has been made Honoris Causa doctor of the University of Liège. Followed by a geeat meeting with him at GIGA on this occasion @GIGA_ULiege@UniversiteLiege@frsFNRS
🦠 For the next FRESK seminar on monday, December 9th, we meet Suchismita Das (LPENS) for the next presentation: "Active colloidal matter: flocking and wetting transitions"
https://t.co/PzZxVTSUZm
🚨 We’re hiring! 🚨 We're looking for a postdoc for our ERC Synergy project Unfold (https://t.co/SK9mZdyGaN). Join our lab at @institutpasteur to model brain morphogenesis! (1/10)
Ce vendredi midi, la Caisse des Écoles de Paris Centre adopte le Croc de #notrecafemarais. 🙏à tous ceux qui ont participé à cette initiative et 👏à notre belle équipe Steeve, Nadine et Anastasia en cuisine à l’école de la place des Vosges.
#accessibiliteuniverselle
🧠 Come work with us! Our lab at @institutpasteur
looks for a postdoc to help us create the most complete open atlas of brain folding development! This is part of our ERC Synergy project Unfold (https://t.co/SK9mZdyGaN). Join us! (1/10)
Interested in the development of brain folding? We have 2 postdoc positions to study the molecular and mechanical causes of brain folding!
Thread 1: Modelling different hypotheses of brain folding
Thread 2: Multimodal, multi-scale atlas
@BorrellLab@neuroliege@Franze_Lab (1/3)
🚨 We’re hiring! 🚨 We're looking for a postdoc for our ERC Synergy project Unfold (https://t.co/SK9mZdyGaN). Join our lab at @institutpasteur to model brain morphogenesis! (1/10)
🧠 Come work with us! Our lab at @institutpasteur
looks for a postdoc to help us create the most complete open atlas of brain folding development! This is part of our ERC Synergy project Unfold (https://t.co/SK9mZdyGaN). Join us! (1/10)
📜 Profile: Neuroscientist with a quantitative background (eng/comp sci/maths), with experience working with pixels, voxels and meshes, computational neuroanatomy, programming skills (Python, Javascript) and passion for brain development 🔗 DM for info! Spread the word! (10/10)