REPLAYproject

REconnecting PLAstics life cycle to biogeochemical cycles by sustainable hydrolysis and Yeasts fermentation

[REPLAYproject @REPLAYproject_]

Sei uno studente interessato a una delle sfide maggiori del nostro tempo: la gestione responsabile dei rifiuti plastici? Non perdere l'opportunità di partecipare al nostro webinar!
📅 29 maggio
⏰ 14.30-16.00
📍Piattaforma Zoom
Per info e registrazioni👇https://t.co/DqcG2ESAST

[REPLAYproject @REPLAYproject_]

The research unit of @unibait also has the task of physiological characterize the engineered cells in collaboration with the research unit of @unimib that will develop in silico metabolism models of Yarrowia lipolytica.

[REPLAYproject @REPLAYproject_]

The Laboratory of Microbial Biotechnology of the @unibait is also part of the #REPLAY project with the task of engineering yeast cells of Yarrowia lipolytica to assimilate and use PET depolymerization products such as TPA and EG to synthesize molecules of industrial interest.

[REPurpose project @REPurposeEu]

Your active participation made the discussion on R&D approaches for sustainable polymers truly insightful and impactful. Special thanks to the collaborators, the @REPLAYproject_ @Proplaproject , and @aimplas for contributing to the success of this event.

[REPLAYproject @REPLAYproject_]

🟢 RESEARCH GRANT AVAILABLE! 🟢
Project partner @IndBiotechEU from @unimib is looking for master's graduates or post-doc fellows to work on the #REPLAY project!
To apply or to learn more, visit https://t.co/KNeGbjy8S2  and submit your application before the respective deadlines.

[REPLAYproject @REPLAYproject_]

In particular, IndBiotech Lab is employing metabolic engineering approaches and synthetic biology tools to rewrite the metabolism of Saccharomyces cerevisiae, the well-known workhorse in the field of yeast fermentation. ‌

[REPLAYproject @REPLAYproject_]

The REPLAY Project, started in June 2022, is currently over one year in operation, and all research groups are actively working to achieve the objectives previously set.

[REPLAYproject @REPLAYproject_]

The activities of @unimib , with the #IndBiotech Lab focus on metabolizing terephthalic acid (TPA) and ethylene glycol (EG) deriving from PET hydrolysis from by yeasts fermentation.

[REPLAYproject @REPLAYproject_]

in this way REPLAY project will generate a SIGNIFICANT SCIENTIFIC, and TECHNOLOGICAL ADVANCEMENT in PET upcycling, enabling engineered #microorganisms🦠 and #yeasts to convert PET degradation products into organic acids.
[3/3]

[REPLAYproject @REPLAYproject_]

REPLAY wants to reduce the negative environmental 🌍 and economic outcomes generated by #plastic disposal practices. The project aims to realise a new concept of plastic (bio)refinery in which post-consumer plastic #waste can be seen as a feedstock for microbial activity.
[1/3]

[REPLAYproject @REPLAYproject_]

The main objective is to develop an innovative plastic waste-based process to avoid the down-cycling treatments of plastics and promote the upgrading♻️ of #PET waste through the implementation of the use of synthetic biology, (bio)chemical, and (bio)process engineering.
[2/3]

[REPLAYproject @REPLAYproject_]

[3/3] for PET pre-treatment and with the discovery of #enzymes able to degrade PET, PE and PP.
#REPLAY aims at #PET sustainable depolymerisation and fermentation as a principle for fostering the reconnection of fossil resources with the biogeochemical cycles of elements 🌍

[REPLAYproject @REPLAYproject_]

[1/3] The basic constituent plastic polymers are dominated by polyethylene (PE), polypropylene (PP), polystyrene (PS), and polyethylene terephthalate (PET), counting for more than 75% of global #plastics production🥤.

[REPLAYproject @REPLAYproject_]

[2/3] The prospects of using green chemistry principles and #enzymatic biodiversity for the #sustainable degradation of traditionally non-biodegradable plastics is now coming real after the last advances with the use and formulation of nature-inspired (DESs)

[REPLAYproject @REPLAYproject_]

#REPLAY aims at demonstrating that the hydrolysates / depolymerisation products deriving from end-use traditional #plastics can be considered as feedstock not in competition with food to be provided to microorganisms to be sustainably upgraded to virgin chemical platforms.

[REPLAYproject @REPLAYproject_]

Monomers derived from #PET depolymerization, a basic constituent polymer of plastics, can be upgraded by engineered #microorganisms 🦠 in useful chemicals such as carboxylic acids, addressing the logic of rethinking and pursuing the goal of “zero #waste”.

[REPLAYproject @REPLAYproject_]

2/2 waste produced in the world 🥤. The #REPLAY project aims to valorise the #PET degradation products, enzymatically or chemically generated, to create a novel value chain, and a hybrid refinery model that will introduce plastics into the #CircularEconomy🌍.

[REPLAYproject @REPLAYproject_]

Even though the plastic industry produces a broad range of plastic products, the basic constituent polymers are dominated by PE, PP, PS, and PET. The post-consumer #plastic waste is mixtures of these plastics that altogether amount to 200 Mt, constituting 70% of the total plastic

[REPLAYproject @REPLAYproject_]

What do the deepest point in the ocean and the highest mountain peak have in common? Plastic pollution.
This can and must be changed!
Ahead of #WorldEnvironmentDay, join @UNEP in calling for accelerated progress to #BeatPlasticPollution.

#REPLAYproject

[REPLAYproject @REPLAYproject_]

He was lucky enough to talk in one of the recorded sessions, in the biggest hall of the Conference Center. Here the link to watch him.
https://t.co/kGhqIbOmdh

[REPLAYproject @REPLAYproject_]

Our PhD Vittorio Senatore attended the Annual Conference of the Microbiology Society in Birmingham and presented his work in an offered oral #talk: "Yeast fermentation for the upcycling of PET monomers" where he discussed the latest results of the REPLAY project.