Newly validated tiny #riboswitch RNAs sense the #thiamin#vitamin precursor HMP-PP. The riboswitch #aptamer is mostly hidden in a transcription terminator stem. Details, including tandem genetic logic gates, are on-line @eLife. https://t.co/jyZS8Mzbo3
Higher-order RNA structures are pervasive and involve more than one-third of nucleotides in the dengue virus serotype 2 (DENV2) genomic RNA. These could possibly serve as novel RNA-directed drug targets! https://t.co/mr2RdRZ4fD
The BGSU RNA Group would be offering a workshop on RNA structure visualization and analysis during the 20th Rustbelt Meeting (@RRM_RNA). See you in Columbus! https://t.co/62xqC1sOd2
If some #riboswitch#aptamer RNAs are molecular relics from the #RNAWorld, then new x-ray structures of RNAs bound to ppGpp and PRPP by Peselis and Serganov in @nchembio give us another glimpse of the body parts of our most ancient ancestors. https://t.co/jkKVNf8QRW
Eric Westhof: RNA Puzzles can only work if modelers keep quiet about the molecules being solved.
RNA Puzzles toolkits https://t.co/dHDJqPyuwt
New: the unknown Rfam puzzle
New Metrics to compare predictions based on interaction networks.
#RNABenasque2018
New coloring option based on Real Space R (RSR) and RSRZ are now available in the 3D viewer across BGSU RNA pages. Here are some examples: i) https://t.co/Q9yRjYh9A8 and ii) https://t.co/WzY3BPMSz6
Targeting the stem-loop RNA structure TSL2, which overlaps with the 5′ splicing site of exon 7 in survival motor neuron 2 (SMN2) gene reverses spinal muscular atrophy molecular phenotypes https://t.co/qNkJt1ByeV
Disruption of a stem-loop structure located upstream of pseudoknot domain in Tobacco mosaic virus enhanced its infectivity and viral RNA accumulation https://t.co/eehNwuVD0t