Karousis Lab

mRNA translation and degradation group leader in Bern, viral proteins vs human translation - Nanopore seq-curious and very much into teaching - 🏳️‍🌈

[Karousis Lab @RNAkook]

Time to switch... KarousisLab in 🦋

[Ruben Gonzalez @rubenlgonzalez]

Our latest work is out in @Nature today! Using smFRET, we directly visualized recruitment of the eIF4F complex to the 5' cap of eukaryotic mRNAs and formation of an activated mRNA. Our findings reveal new and surprising roles for each eIF4F component. 1/3 https://t.co/THosKn33fC

[Karousis Lab @RNAkook]

New pre-print 📢:Cell-free translation from diverse human cell types: Fast, reproducible and scalable @JZiegelmuller @OMuhlemann @MCIDBern @DCBPunibern @unibern https://t.co/IAld0ocjDf

[Karousis Lab @RNAkook]

@lapassmore Great work with very exciting insights, congratulations!

[Lori Passmore @lapassmore]

Preprint here: https://t.co/khiLFPwXGs

[Karousis Lab @RNAkook]

@LabFaso @unibern @DCBPunibern @NCCR_RNADisease @MCIDBern Thanks a lot, Carmen! 😄

[Karousis Lab @RNAkook]

#Habilitation done! 🎉 I’m grateful and proud to receive the Privat Dozent title from @unibern, an institution with a special place in my heart. I'll strive to stand as an ambassador of its values in sharing my passion for Biochemistry and Molecular Biology. @DCBPunibern

[Karousis Lab @RNAkook]

@Jonathan_Bohlen Thanks Jonathan! 😄

[Karousis Lab @RNAkook]

@nicolamlow Sometimes, it's almost impossible to find a snack that won't ruin your nutritional goals!

[Karousis Lab @RNAkook]

6/ We conclude by addressing the (co)-evolutionary interplay between Nsp1 and the 5'UTR from different Betacoronaviruses🦠

[Karousis Lab @RNAkook]

1/ Preprint alert📢: Uncoupling the functional roles of Coronavirus Nsp1
https://t.co/eyM3c70DZY #biorxiv_molbio
Doubly excited because this work is based on our first Master's student to graduate from the lab, Emilie Bäumlin.
@unibern @DCBPunibern @MCIDBern @NCCR_RNADisease

[Karousis Lab @RNAkook]

5/ We evaluated Nsp1 previously proposed Nsp1 inhibitors, Montelukast and Mitoxantrone, finding them ineffective against Nsp1’s ability to inhibit translation. 🚫

[Karousis Lab @RNAkook]

Thrilled to see @Jonathan_Bohlen, starting his group, very, very well deserved!

[Jonathan Bohlen @Jonathan_Bohlen]

It's a very special day for me. I am so excited and grateful for this opportunity. My lab will study the role of mRNA translation in human immunity. Reach out if you're interested to join us. @GeneCenter_LMU @LMU_Muenchen

[Mühlemann Lab @OMuhlemann]

Please RT: Are you a highly skilled, top-motivated biochemist looking for an exciting postdoc project? We are looking for you. For details, check here: https://t.co/qn2vi5PkEt

[Karousis Lab @RNAkook]

Is Science Direct down for everyone? Any ideas how to circumvent it when doing doi-based paper searches?
#sciencedirect #AcademicTwitter #AcademicChatter

[David R. Liu @davidrliu]

Today we report in @natBME the eePASSIGE system, which uses evolved and engineered recombinases and prime editing to integrate large gene-sized DNA cargoes into the mammalian genome in an efficient, precise, and targeted manner. (1/13)
https://t.co/xvjTwgApde

[Green Lab @GreenLabJHMI]

We’re excited to share our study in @CellCellPress on the role of the MAP3 kinase ZAK in UV-induced apoptosis led by @2primehydroxyl! We studied cell signaling kinetics following UV-damage and found that ZAK drives apoptosis via ribosome collisions. https://t.co/A3RjOkq62k