Kersten Rabe

Enthusiastic about Biocatalysis, Evolution and Extremophiles. Loves gradients, microengineering and meditation. @KITKarlsruhe @NiemeyerLab. Views are my own.

[Kersten Rabe @RabeKersten]

Imagine you could visualize the stress of microbes using a rainbow of fluorescent proteins! Our RGB-S reporter, a plasmid that monitors different stress types in real-time is now available through addgene: https://t.co/ddBEXsDoFX

The paper: https://t.co/vvlWR7AUzZ

[Kersten Rabe @RabeKersten]

@Nature_NPJ @NiemeyerLab Thanks for highlighting our research! The RGB-S plasmid is now available at Addgene: https://t.co/uLqOKkwQXE

[Kersten Rabe @RabeKersten]

@EvolvedBiofilm @KITKarlsruhe Thanks for highlighting our research! The RGB-S plasmid is now available at Addgene: https://t.co/ddBEXsDoFX

[Kersten Rabe @RabeKersten]

@nfanget Thanks for highlighting our research! The plasmid is now available at Addgene: https://t.co/ddBEXsDoFX

[Nicolas Fanget @nfanget]

New article! Read A three-colour stress biosensor reveals multimodal response in single cells and spatiotemporal dynamics of biofilms in npj Biofilms https://t.co/xkKijWSzmP

[Kersten Rabe @RabeKersten]

@EvolvedBiofilm @KITKarlsruhe Thank you for mentioning our work so prominently here 😀 Since there have already been a few enquiries: we are currently in the process of depositing the plasmid with Addgene. I will post here as soon as it is available there.

[Advanced Portfolio @AdvPortfolio]

These microbubbles are further processed to become monodisperse foams that consist almost entirely of enzymes.

These foams work as stable, highly active biocatalysts @RabeKersten @NiemeyerLab @KITKarlsruhe

👉 https://t.co/CTvo1Ljy16

[Kersten Rabe @RabeKersten]

Enzymes and foams? Great idea?
Contrary to what we probably all learned in basic biochemistry class, foamed enzymes can be used to produce extremely stable biocatalytic materials.
Check out the paper
https://t.co/3m2wU18rZa
and the corresponding german press release.

[Kersten Rabe @RabeKersten]

Congratulations to Esther Mittmann who won a well deserved poster prize at #Biotrans2023! Anaerobic flow biocatalysis is not easy, but continuous transformation is the key to establishing new-to-nature reactions for future industrial applications!

[Kersten Rabe @RabeKersten]

@RastegarS1 May the reviewers be with you 😀

[Kersten Rabe @RabeKersten]

#Biotrans2023 has offered us much science and fun 😊 Thanks a lot to the organizers and Julian Hertel, Felix Ott, Esther Mittmann, Astrid Winterhalter, Marius Stöckle for representing IBG-1 !

[Kersten Rabe @RabeKersten]

#biotrans2023 Today we have three more posters for you on thermostable enzymes (Marius, 1222), use of ITC for enzyme modeling (Felix, 1392) and self-immobilizing enzymes (Astrid, 1414). Be sure to check them out 😀🧪🦠👩‍🔬🤓

[Kersten Rabe @RabeKersten]

Finally on my way to LaRochelle! L
Looking forward to great science and happy to presen our work on a new biocatalytic material on Thursday 😀
While I am traveling, talk to my colleagues Esther and Julian presenting poster 1229 and 1393 today, more posters tomorrow
#biotrans2023

[Kersten Rabe @RabeKersten]

Our Paper "An Immobilised Silicon-Carbon Bond-Forming Enzyme for Anaerobic Flow Biocatalysis" is now fully published!

[ChemCatChem @ChemCatChem]

📢Check out Issue 9: https://t.co/Kp8QQcZcen

Featuring cover articles by Emiel Hensen & Chularat Wattanakit and @giustiniano & @Davide_Rv.

Including work by @GroupLese, @RoseGroup1, @Jedrzej_ASCLab, @JoseMPalomo1, @PalkovitsLab, @NiemeyerLab & @RabeKersten, and many more.

[Thomas van de Kamp @Thomas_vdKamp]

OPEN POSITION - Join our team @KITKarlsruhe and @UniHohenheim for the development of #robotics to enable serial #xray #tomography. If you are interested, check out the #joboffer: https://t.co/B0WlsaPMKp #joboffers #jobsuche #roboter #robotik #automatisierungstechnik #automation

[GBM e.V. @GBM_eV]

📢GBM Compact: Focus on Proteomics 👉Registration is open at https://t.co/VKpLp7KHkm Register and submit your abstract now! Short talks will be selected from the abstracts! Also, two poster prizes (300 Euro each) will be awarded; Join us in Frankfurt for an exciting conference🤩

[Kersten Rabe @RabeKersten]

Super happy to be part of the YI@GBM board, ensuring that early career scientist, post-doc, group leader etc are also being heard. Great team 👩‍🔬🧑‍🔬👨‍🔬

[Thomas van de Kamp @Thomas_vdKamp]

OPEN POSITION - Join our team @KITKarlsruhe for #deeplearning based #simulation of #xray #tomography to enable training of algorithms for processing time-resolved tomography.
Check out this link to learn more: https://t.co/SYLfvI9wQs

[Kersten Rabe @RabeKersten]

How to increase total turnover numbers of new-to-nature enzyme reactions? Integrate them into flow reactors to enable continuous conversions, check out our paper in @ChemCatChem thanks to the hard work of Sabrina Gallus, Esther Mittmann and Annika Weber 👍

[ChemCatChem @ChemCatChem]

An Immobilised Silicon-Carbon Bond-Forming Enzyme for Anaerobic Flow Biocatalysis by Kersten S. Rabe and co-workers (@NiemeyerLab, @RabeKersten). #OpenAccess thanks to #ProjektDEAL. https://t.co/MlfFTZRCiM

[Kersten Rabe @RabeKersten]

Looking forward to fixing the substrate solubility and drop in stereoselectivity next 🧪🤓
Thanks: German Chemical Industry Association VCI for the support of Kekulé Fellows Sabrina Gallus (former) and Annika J. Weber (current) and @ChemCatChem for the fast publication process!

[Kersten Rabe @RabeKersten]

We moved the new-to-nature biocatalytic production of organosilicones developed in the laboratory of @francesarnold into a continuous reaction setup under anaerobic conditions. Result: TON up six-fold and much higher STY ⬆️⬆️👍

https://t.co/t0ngtu0hw2

[Kersten Rabe @RabeKersten]

Second part: We also learned a lot more about the solubility and stability of the substrates and understood what is important for the continuous synthesis of organosilicones under anaerobic conditions.