Predictions for the future of medicine
- Unprecedented rates of remission in autoimmune disorders
- More precise drugs
- Disease-modifying medicines for previously untreatable diseases
- Faster trials, using surrogate endpoints
Full version here! https://t.co/4R6Kmn1O7s
Applications are now open for the International Collaboration for Research methods Development in Oncology (CReDO) Workshop—a six-day residential oncology research protocol development workshop.
(1st–6th March 2027).
Application deadline: 31st July 2026.
I strongly encourage oncology residents, fellows and early-career faculty with an interest in clinical research to apply.
Don't be deterred by the listed fee—most selected participants receive ~90% fee support through external grants.
#CReDO @OncoDaily@cspramesh@OncBrothers@oncology_bg@SirohiBhawna
The academia equivalent of this is, everyone is expected to generate high volume, high quality research output.
The ordinary teacher, who loved teaching, focused on student experience, is fast becoming a relic of the past
Interesting observation. Chennai has significantly higher life satisfaction and happiness score than national average.
What is surprising is these scores are even better than US and UK national averages.
This week in medicine
1. A synthetic lethal approach adds to RAS inhibition in pancreatic cancer
2. A potentially best-in-class ulcerative colitis drug
3. Discovery of a defined autoimmune subtype of inflammatory bowel disease
4. Genetic therapies for sickle cell keep working
5. More data on muscle-sparing weight loss
This is the silent part that people wouldn't know.
Behind closed doors inside a medical conference, a large group of clinicians and researchers giving a standing ovation to another group of clinicians and researchers who found a way to increase survival in patients suffering from one of the, if not the, worst cancer in humans.
Metastatic pancreatic cancer.
They'll do this and then be on their way to see their patients the next day as if nothing happened.
And then work on something new to better what they did in this room.
That is how medical science works.
Value it and value its practitioners.
Mainstream media may never raise this issue.
But cancer patients across India are paying the price every single day.
No cisplatin. No carboplatin. Delayed chemotherapy. Families waiting helplessly.
If independent voices don’t speak now, who will?
Please repost. Make noise. Force attention.
Because silence is also harmful.
#OncoTwitter #MedTwitter #CisplatinShortage #drugshortage
#NotAllNewsIsNews
@PMOIndia@JPNadda@newslaundry@TheDeshBhakt@ravish_journo@Cockroachisback@RahulGandhi@theliverdoc
Today is International Nurses Day, the birth anniversary of Florence Nightingale.
While everyone knows about her nursing , she was adept at statistics.
When she arrived at Crimean War front in 1854, she found too more men dying from cholera and typhus, than on the battlefield.
The numbers were dry and didn’t convey the enormity of the problem. She made a version of pie chart and called it Coxcomb chart (what we call as polar area chart today). It showed how 16000 of the 18000 deaths were preventable !
The chart captured the imagination of the British parliament and Queen Victoria herself. It’s the data visualization equivalent of a blockbuster. It led to formation ofRoyal Commission on the Health of the Army in 1857 , changed hospital design, introduced evidence based nursing, Public Health Act of 1875 and showed that nurses save lives, in more ways than one.
Nightingale became the first woman to become a member of Royal Statistical Society.
Pic - the original “rose chart” published made by Nightingage in 1858
Here is the inside story on how @UpToDate does what it does.
From my experience as an author/section editor for UpToDate for 20 years, here is how it works. It’s amazing!
Every day a team of people @UpToDate scour the top medical journals (and major meeting abstracts) for articles of importance. In my case they pertain to myeloma and related disorders. Any article that is felt to be important is sent to a expert MD medical editor at UpToDate who reviews the paper. If the information is felt to be important, the relevant chapter is updated with this content, summarized in a few sentences in Word track and then sent to the author of the chapter who is a top expert in the field.
As an author I have to review the update in detail and then make a decision whether to include the new information, and whether the way it has been incorporated is correct or needs to be edited.
Once I make a decision, it is then reviewed by an expert section editor. For 15 years for me, the section editor was Dr. Robert Kyle! (Currently I’m the section editor and we have about 6 experts serve as authors on over 40 chapters pertaining to myeloma and related disorders). The section editor independently decides whether the author made the right call and either approves or we have a back and forth till we agree.
The updated chapter is then reviewed again by the expert MD editor at UpToDate and then posted.
For important phase III trials or FDA approvals we usually make the update within a week. Sometimes by the next day! With so many important papers, every week there are 2-3 updates pertaining to my chapters that go through the above process! It’s hard work but it keeps me ridiculously current. And more importantly it keeps the content accurate and current. This is not random addition of new information. It’s vetted information that’s added.
Every UpToDate chapter is also peer reviewed annually. Each chapter also undergoes an annual author and editor review to make sure that the overall content and flow is good and to delete content that may be no longer important or accurate. The extraordinary process and rigor involved is why it’s such an invaluable irreplaceable resource. It is AMAZING and hard to replicate.
UpToDate is easy to navigate. But the newly launched UpToDate Expert AI takes it to the next level! It makes the entire content available to query just like you query a top ranked LLM. But it’s not searching the random internet or a stack of published articles. It’s primarily trained and derives vetted and adjudicated UpToDate content. It will not randomly hallucinate. It will not list 10 options for treatment newly diagnosed myeloma but will give you what experts currently feel is the best option based on the latest evidence. All answers are referenced and pointing to specific content sections in UpToDate (which also has links to source material). So you can immediately get all the background information if you need more detail.
Working with UpToDate has helped my career immensely. For the last 20 years it has been impossible for me to not know about every important study related to myeloma and related disorders as they get published! For 20 years, I have received a precise summary of every important article published in my field. More importantly I am forced to read them, review the source material, and make a judgment call. As a result I remember this stuff. A gift indeed!
His name was V Rajaraman.
Born in 1933 in Erode, Tamil Nadu. Most Indians have never heard his name. Every Indian IT professional owes their career to him.
He studied physics at St Stephens College Delhi, then engineering at IISc Bangalore. Won a government scholarship to MIT. Got his PhD in 1961.
The world wanted him. He came back.
In 1963, a massive IBM 1620 computer arrived at IIT Kanpur. It was so large they had to break down a wall to bring it inside. It came on a bullock cart.
Rajaraman stood next to it and asked one question nobody else was asking.
What if India taught this as a subject.
In 1965, he launched India’s first Computer Science academic programme at IIT Kanpur. His first batch had 20 students. One of them was Narayana Murthy, who went on to build Infosys.
He designed the MCA programme that opened IT careers to an entire generation of Indian graduates. He chaired the committee that created C DAC to build India’s first indigenous supercomputers.
He authored 23 textbooks. Guided 30 PhD students. Won the Padma Bhushan in 1998.
He passed away on November 8, 2025. Aged 92.
India’s IT industry is worth 250 billion dollars today. He built the classroom it started in.
Follow for real stories India never makes headlines about.