Mike B

[Mike B @ReDevil1988]

@BradSchoenfeld Studies from these countries are always puzzling… but they never get reproduced

[Mike B @ReDevil1988]

@DanielBerglind Cross section with ultrasound measurement is not considered a direct measurement since water (creatine) can increase CSA and give a false positive effect. That’s why creatine is so good at increasing lean body mass, but when measuring with MRI, it’s pretty much useless

[Mike B @ReDevil1988]

@DanielBerglind Muscle activation ≠ hypertrophy

[Mike B @ReDevil1988]

@DanielBerglind Article doesn’t mention muscle mass anywhere. Where does the bigger gains come from?

[Mike B @ReDevil1988]

@DanielBerglind Artifact in measurement. It doesn’t really matter:

https://t.co/QbCsYH7IDL

[Mike B @ReDevil1988]

@BrandonLuuMD It doesn’t matter. The difference is an artifact in measurement:

https://t.co/QbCsYH7IDL

[Mike B @ReDevil1988]

@zaknight why?

[Mike B @ReDevil1988]

@Jozo_Grgic Very flimsy research design. Basically uncontrolled diet plan with very inaccurate body composition methods

[Mike B @ReDevil1988]

@nicknorwitz @BioLayne What do you expect from someone who writes that the average human has 1000g of glycogen? He just blocked me when I told him that this is pure wrong. Shame on his PhD…

[Mike B @ReDevil1988]

@AlpacaAurelius Nice cherry picking

[Mike B @ReDevil1988]

@DanielBerglind I would argue it’s one of the worst reviews I read this year. Very inaccurate and full of author’s wishes rather than science…

[Mike B @ReDevil1988]

@DanielBerglind There is actually no effect
both dosage groups showed significant increases, with no statistically significant difference between them:
- Doses ≤5 g/day: WMD: 0.77 kg (95% CI: 0.46 to 1.08, p < 0.001)
- Doses >5 g/day: WMD: 0.89 kg (95% CI: 0.49 to 1.29, p < 0.001)

[Mike B @ReDevil1988]

@KevinH_PhD @JAMA_current @CatConte_MD decrease in SMM induced by weight loss is mediated primarily by an increase in muscle protein breakdown, not a decrease in muscle protein synthesis,

I think the MPS part is not that accurate… MPS decreases by quite a bit..

[Mike B @ReDevil1988]

@martykendall2 If the calorie intake was real in this dataset, there was no global obesity epidemic. Most countries in this dataset report to eat less than 2,000 kcal/day. There are many research papers showing how people are pretty bad at reporting how much they eat, even with MFP/other apps.

[Mike B @ReDevil1988]

@DanielBerglind 4 weeks ;(

[Mike B @ReDevil1988]

@davidludwigmd Based on the p value and CI, the statement about fat seems like a wishful thinking of the authors rather than actual “truth”.

[Mike B @ReDevil1988]

@maxlugavere Because Nutritional “science” + associations = crap science

[Mike B @ReDevil1988]

@martykendall2 Overall, I would argue that being so absolute about protein intake and kidney damage is probably not accurate based on the current research.

The statement should probably be: higher protein intake is *probably* not detrimental for healthy young adults in the *short term*.

[Mike B @ReDevil1988]

@martykendall2 4. There are longer studies, but they are observational studies, so the quality is lacking.

5. We also need to understand that It's technically and financially impossible to control intake precisely for two years.

[Mike B @ReDevil1988]

@martykendall2 1. We don't really know if the subjects **actually** ate 4.4g/kg protein during the entire research duration.

2. These were healthy young adults.

3. I don't think it's relevant practically or beneficial to eat such a high amount of protein daily.