Han Remaut

[Nature Microbiology @NatureMicrobiol]

Out Now! Peptidoglycan–outer membrane attachment generates periplasmic pressure to prevent lysis in Gram-negative bacteria https://t.co/U6f1X6AIli #Peptidoglycan #BacteriaResearch #Microbiology

[Han Remaut @RemautHan]

@CostaT_Lab @jrpenades I’ll set my alarm ⏰ 🤩

[Tiago Costa @CostaT_Lab]

@RemautHan @jrpenades Thanks, Han! More exciting news coming next week!

[RadfordLab @RadfordLab]

Great opportunity to join the Radford / Ranson labs and the world-renowned Astbury Centre as a Research Fellow in Structural Biology! Please see https://t.co/9ILjd76AK8

[Han Remaut @RemautHan]

@VIBConferences @structbiolbxl @TrendsinBiotech @deboracferreir @EngBiologicaUM @EMBO Congratulations Vita, Sylvia & Lander. Great job !!👏

[Han Remaut @RemautHan]

@santin_yoann @deDuveInstitute @LalouxLab Scary 😱😅

[VIB @VIBLifeSciences]

🤯 Specific strains of 𝘌. 𝘤𝘰𝘭𝘪 might contribute to colon cancer. @LarsVereecke @RemautHan @MaudeJans @magdalenakolata and colleagues figure out how.
➡️ Read here https://t.co/ldDtT7KJLJ
@InflamResCen @structbiolbxl @ugent @VUBrussel @FWOVlaanderen @Stkstichting @crighent

[Lars Vereecke @LarsVereecke]

5/6 This was a fantastic collaboration with the @RemautHan lab. Thanks to all who contributed to this work, including @IlievLab, @Joharrr, @SabineTejpar, @GeertBerx 🙏🙏🙏

[Lars Vereecke @LarsVereecke]

🔍 Huge thanks to @kyannaouyang and @JensPuschhof for their insightful News and Views perspective on our study! 🙏🤩

https://t.co/ACRmoRwI1m

[Lars Vereecke @LarsVereecke]

6/6 Special thanks to @Stkstichting , @FWOVlaanderen , @VIBLifeSciences , @crighent, @ugent ,@VUBrussel and @InflamResCen for funding and supporting our work. 🧪🙏🙏

[Han Remaut @RemautHan]

The feeling is completely reciprocal, absolute pleasure and boost to collaborate with @LarsVereecke lab

[Lars Vereecke @LarsVereecke]

5/6 This was a fantastic collaboration with the @RemautHan lab. Thanks to all who contributed to this work, including @IlievLab, @Joharrr, @SabineTejpar, @GeertBerx 🙏🙏🙏

[Lars Vereecke @LarsVereecke]

4/6 🚨 Our findings raise concerns about using E. coli Nissle 1917 as a probiotic. Minimal mutations in Nissle FimH can transform this pks⁺ strain into a highly genotoxic one, potentially increasing cancer risk. A re-evaluation of its safety as a probiotic may be warranted. 🧬⚠️

[Lars Vereecke @LarsVereecke]

3/6 Pharmacological inhibition of FimH effectively blocks bacterial binding, reducing genotoxicity and colon cancer progression. This targeted approach spares beneficial gut microbes, offering a promising therapeutic strategy without the drawbacks of antibiotics. 🚫💊

[Lars Vereecke @LarsVereecke]

2/6 Our study reveals that the adhesins FimH and FmlH are critical for pks⁺ E. coli to bind epithelial cells, enabling colibactin production in close proximity to host DNA. This binding significantly amplifies DNA damage, driving colon cancer development. 🦠🔬

[Lars Vereecke @LarsVereecke]

🎉 Super excited to announce that our study "Colibactin-driven colon cancer requires adhesin-mediated epithelial binding" is now published in Nature! Huge congratulations to first authors @MaudeJans and @magdalenakolata for their fantastic work! 1/6🧵🎉
https://t.co/mhCUpxsKXX

[Han Remaut @RemautHan]

@AnnaDuraj @VUBrussel Was a real pleasure to welcome @AnnaDuraj to VUB - @structbiolbxl and hear her discuss the future of protein materials.

[Anna Duraj-Thatte @AnnaDuraj]

I had a great time discussing functional amyloids and presenting my work on #EngineeredLivingMaterials at Vrije Universiteit Brussel @VUBrussel

Thanks, @RemautHan, for hosting me!

[RadfordLab @RadfordLab]

Post doc in cryo EM of Amyloid- with @naranson and @AstburyCentre- an exciting opportunity for you to join our collegiate and inspiring team trying to crack amyloid disease by better understanding its formation from test tubes to tissues. Apply here

https://t.co/J4y8XDo65f

[NO CONTEXT HUMANS @HumansNoContext]

His accuracy is 100/100