Klaudia Gomez

Rheumatologist | MSK Ultrasound | 🇲🇽

[Dr. John Cush @RheumNow]

Korean retrospective study compared NIDDM pts Rx w/ SGLT2 inhibitor (n 552,065) vs sulfonylurea (1,480,092) showed SGLT2 inhibitors were assoc w/ a signif 11% lower risk of incident autoimmune rheumatic disease (HR 0.89). Diff of −6.50 per 100K PYs over median ~9 mos F/U. https://t.co/fKo4aQV1n2

[Dr. John Cush @RheumNow]

Nailfold Capillaroscopy correlated w/ cardiac ECHO in Systemic Sclerosis. NFC & ECHOs studied in 30 SSc pts. Systolic & diastolic dysfunction most common in late SSc NFC patterns. Cardiac dysfunction seen w/ low capillary density, avascular areas, cap neoangiogenesis https://t.co/j8xKpSlUoI

[Sᴡɪss Uʟᴛʀᴀsᴏᴜɴᴅ Cᴇɴᴛᴇʀ - UZR @Rheumatology]

ARTHRITIS IMAGING

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https://t.co/wZy61dfdcN

[Abdulwahed AL zaher @MSKUS_PT_KSA]

A_3 pulley with slight tenosynovitis
صوره من ورشه العمل.

[Dr. John Cush @RheumNow]

Full read review of Catastrophic Antiphospholipid Syndrome (CAPS) https://t.co/J1kOJYv1Cl

[Janet Pope @Janetbirdope]

Many treatments for seronegative #spondyloarthropathy. And #psoriatic #arthritis But what to choose and when and for whom?

[Dr. John Cush @RheumNow]

SGLT2 inhibitor (empagliflozin) given in a lupus mouse (MRL/lpr) model showed a renoprotective effect suggesting the value of non-immunosuppressive therapies to improve renal function. Showed less -dsDNA Abs, proteinuria, renal nephritis damage https://t.co/uJjr7rTIJe

[Dr. Samir Nusair, MD 🇮🇱 @SamirNus]

Data from 'real-world' experience suggest that Nintedanib could be helpful for patients who start treatment after presenting with ILD acute exacerbation decreasing the occurrence of recurrent exacerbations and prolonging survival.
#pulmonaryfibrosis
https://t.co/RxhEn8O0Uj

[Cristina Macía @reumacia]

Revisión narrativa 📚 de los tratamientos disponibles para artritis psoriásica por dominios y enfermedades asociadas. Gran trabajo de @drgizemayan @Dr_AndreRibeiro @BetulMacit @ProftDr @GrappaO 👏🏻 Enlace abierto 🔓 https://t.co/UJJAALk1V6

[Klaudia Gomez @ReumaPOCUS]

@OrlandoRPN El famoso artri king contiene que contiene dexametasona , a reúma llegan los pacientes con cushing y aparte inflamados

[Dr. John Cush @RheumNow]

Tofacitinib May Reduce Interstitial Lung Disease Risk in RA

Tofacitinib (Xeljanz) in patients with RA stood out among several other biologic and targeted sDMARDs when it came to the incidence of ILD, a retrospective cohort study showed.

https://t.co/XKjuxLWAKH

[Klaudia Gomez @ReumaPOCUS]

@xfraaa Sertralina

[Jose Luis Morell @JlMorell]

Peripheral Blood Biomarkers for Rheumatoid Arthritis-Associated Interstitial Lung Disease: A Systematic Review https://t.co/et8vqpxMDI

[Rohit Aggarwal @docrota]

#MyositisPearl 8: A subtype of #Myositis is Immune Mediated Necrotizing Myopathy (#IMMM). It is about 20% of all #IIM. It is associated with anti-SRP (1/3rd) & anti-HMGCR (1/3rd) Myositis Antibody. 1/3rd Ab negative. Leads to severe muscle weakness, very high CK and disability.

[Jesús Loarce @JesusLoarce]

Review on scleromyositis:
- No validated definition.
- Aldolase is more frequently elevated than CK.
- Antibodies: anti-PM/Scl, -Ku, -U1-RNP, -U3-RNP, - RuvBL1/2, -SMN
- Muscle biopsy: Vasculopathy, fibrosis, myofiber necrosis.
- Be careful with steroids and SSc renal crisis.

[Klaudia Gomez @ReumaPOCUS]

Que mala atención de @viajaVolaris Merida

[Janet Pope @Janetbirdope]

#ClinicalPearl #MedEd #MedTwitter Elderly woman with long-standing hand pain. What do you think? hint look at L2nd MCP. Bonus - what about bone quality

[Jesús Loarce @JesusLoarce]

Our analysis of myositis specific and associated antibodies (MSA/MAA) detected by line blot in our Immunology lab between 2018 -2020
- 130 samples ➡ 164 MSA/MAA.
- 51.8% were classified as clinical true + (CTP) (associated to their disease) and 48.2% as clinical false + (CFP).

[Jesús Loarce @JesusLoarce]

More evidence on JAK inhibitors in dermatomyositis:
- Open label. 16 patients. 88% cutaneous, 56% muscle, 44% both.
- Improvement in CDASI ➡ 27 (basal) ➡ 14 (3 months) ➡ 5 (1.8 years).
- 1 died (MDA5 with ILD), 2 relapsed (muscle disease).

https://t.co/JMXfMaShip

[Jesús Loarce @JesusLoarce]

Clinical phenotypes in ANCA asociated interstitial lung disease:
- 100 patients. Retrospective study.
- 3 groups: MPA, unclassifiable vasculitis, IPF (ANCA+).
- Unclassifiable vasculitis tended to have a better survival