Richard Matzko

Digital Pathology Postdoc, formerly Clinical Data Science Postdoc, PhD in Synthetic Biology via Computer Science, BSc Biomedical Science

[Richard Matzko @RichardMatzko]

We recently published this review on #AI for #cancer #histopathology through the lens of regulatory approved devices to highlight genuine technical pathways to clinical adoption. The field is evidently still highly nascent.

https://t.co/RmkGvkqqWN

#DigitalPathology #MedicalAI

[Geoffrey Hinton @geoffreyhinton]

I like OpenAI’s mission of 'ensure that artificial general intelligence benefits all of humanity”, and I’d like to stop them from completely gutting it.
I’ve signed on to a new letter to @AGRobBonta & @DE_DOJ asking them to halt the restructuring. (1/2)

[Peter Holderrieth @peholderrieth]

Our MIT class “6.S184: Introduction to Flow Matching and Diffusion Models” is now available on YouTube!

We teach state-of-the-art generative AI algorithms for images, videos, proteins, etc. together with the mathematical tools to understand them.

https://t.co/wDJcM1YTxJ

(1/4)

[Tim Duignan @TimothyDuignan]

Running out of memory used to be a common headache when running molecular simulations with neural network potentials. Not any more. Here Orb is simulating over half a million atoms on a single GPU (H200). This is a fully solvated COVID spike protein. (The trick is to specify  brute_force_knn=False in the calculator.) This is more than an order of magnitude larger than some other universal models. I can get over 7,000 steps of molecular dynamics per day with it.

[Martin Smith @martinalexsmith]

How cool is this? Michal Lipinski from @broadinstitute presenting stacked #Illumina spatial slides of the mouse brain with subcellular transcriptome resolution #AGBTGM

[BowTiedBiotech 🧪🔬🧬 @BowTiedBiotech]

1/ THREAD: Where do mRNA vaccines go after injection?

Lipid nanoparticles (LNPs) are the workhorses of mRNA vaccines, but how do they move through the body?

New PET-CT imaging in rhesus macaques gives us answers. 🧵👇

[Niko McCarty. @NikoMcCarty]

This video shows a subset of ribosomes inside a cancer cell actively translating mRNA molecules.

Each point of light is one ribosome. An image was taken every 3 minutes over a 4-hour period.

[Sriram S @Sriram_S433]

Axons from the cortex arriving at the thalamus in a developing mouse brain, cleared and imaged with @zeiss_micro light sheet #FluorescenceFriday

[England @England]

Fit for a final. 🤍

[Slava Bobrov @slava__bobrov]

Two brain cells having a chat

[Slava Bobrov @slava__bobrov]

neuron trying to connect to other neurons

[UEFA EURO @UEFAEURO]

Stunning from Jude Bellingham 🤸😲

@AlipayPlus | #EUROGOTT

[Imperial CPD @ImperialCPD]

Students attending 'Hands-on #Data #Analysis #Metabolic Profiling' course this week for training in processing and analysing metabolomics data from LC-MS and NMR technologies. Next course is online in Nov/Dec- look out for dates!👇
https://t.co/ukfXmfMKYZ
@tebbels @ImperialMDR

[Richard Matzko @RichardMatzko]

@ImperialCPD @tebbels @ImperialMDR I really enjoyed this course and meeting you all. It was a great opportunity under exceptional, experienced tutelage, and a very pleasantly organized event.

[Vanessa Barone @Vane_Barone]

There are so many hidden gems in our latest paper, which I worked on while in @LyonsLab_SIO @Scripps_Ocean in collaboration with @lmescu @aj_tagua at @ibis_sevilla. @lmescu will tell you all about the scutoids, so I will tell you about the rest https://t.co/0BTQmWl0wm

[Jan Kosinski @jankosinski]

This is the end of the world as we know it, if this is reproducible! The new era of functional modeling has begun. I took a transcription factor with an unknown structure and folded it with its recognition sequence embedded in longer DNA. AlphaFold3 accurately positioned the transcription factor.

[Eric Betzig @Eric_Betzig]

#FluorescenceFriday #cellbiology #bioart
A neutrophilic cell migrating through a 3D collagen mesh at 1.3 sec intervals for 5.5 min, as seen by lattice light sheet microscopy. https://t.co/LmKOXnesge

[Eric Betzig @Eric_Betzig]

#FluorescenceFriday #cellbiology #bioart Mitochondrial dynamics in a cultured pig kidney cell (LLC-PK1) at 3 volumes/min for 97 min by two-photon Bessel beam plane illumination microscopy. https://t.co/KsbXKFcp6j

[Richard Matzko @RichardMatzko]

My review regarding #SyntheticBiology in silico and #automation methodologies was published today based on my #PhD research.

Technologies for design-build-test-learn automation and computational modelling across the synthetic biology workflow: a review

https://t.co/BjU4wNRyRu

[eLife - the journal @eLife]

A new library of stem cells that express a fluorescent protein offers the opportunity to study the precise locations of thousands of human proteins in many different types of cells. https://t.co/YmjTuoCmLQ.