Rogan Grant

Schmidt Science Fellow in the Chandel Laboratory at Northwestern University studying the intersection of mitochondrial dysfunction and neuroinflammation

[Vivek Sagar @viveksagar]

Excited to report that our new paper is out now:
https://t.co/ZhNB4Im8Av

A thread:
We asked how the brain represents odor pleasantness. Are pleasant and unpleasant odors represented on the same neural axis? Our results suggest: not at first, and not as one would assume.

[JCI insight @JCI_insight]

The translational potential of #metformin in #HuntingtonsDisease is compelling: https://t.co/NqME8cH7Nq

Robert M. Friedlander & team report metformin regulates mitochondrial fission, reprograms deregulated metabolism in HD microglia, and controls microglial activation and inflammation in HD transgenic mice.

The image shows traced microglial morphology from striatum of the HD mouse model R6/2 treated with metformin.

[Arjun Raj @arjunrajlab]

Can someone start a journal called “Cell Atlases” so that the rest of the journals can go back to publishing interesting things?

[nature @Nature]

Nature research paper: Mitochondrial l-2-hydroxyglutarate is a physiological signalling metabolite

https://t.co/7VSFjhjAP0

[Rogan Grant @RoganAGrant]

@panomics @DuaneStorey @jmdubs6 @markwbudde @plasmidsaurus Even there (and ignoring maintenance costs) most library prep kits will still put you over

[David Gate @DGateLab]

Excited to share our latest work on ALS neuroimmunology, published today in @NatureNeuro https://t.co/Ewdf2a4ge2

[John Lukens @LukensJohnR]

Aged circulating CD8+ T cells and their secreted factors drive cognitive decline https://t.co/Ih6QYtmNri
@ImmunityCP

[Rogan Grant @RoganAGrant]

Spatial methods have setting new job submission records far too often. Today: 1.7TB of RAM.

[Hadas Weiss @weiss_hadas]

non academics be like what are your plans for the weekend

[Rogan Grant @RoganAGrant]

@LeighGiangreco And we still don't have an O'Hare express

[Jenn🌲 @JuniperFolly]

this is what it feels like to live in chicago

[Rogan Grant @RoganAGrant]

.@ILSecOfState every single one of your appointment scheduling links for the DMV 404s right now. Please fix.

[Kenneth Loi @kenjmloi]

Excited to share our discovery of a new programmable RNA-guided DNA-targeting system hiding inside bacteriophages that predates CRISPR.

We call it VIPR (Viral Interference Programmable Repeat), and it uses an entirely new logic to find its targets.

Thread + link below.

[Eric Topol @EricTopol]

This @NYTmag article on longevity science, reversing aging with cellular reprogramming, by @susandominus, is over the top. We have no proof that rejuvenation of a human organ is possible, no less the whole body, and there is risk of inducing cancer.
gift link https://t.co/VEGpaBncFN

[Rogan Grant @RoganAGrant]

@bakermind

[Dr Terry Simpson @drterrysimpson]

Yes you chased away a lot of scientists, you defunded many programs, and censored others. You are the problem

[Rogan Grant @RoganAGrant]

@other_st_nick @chicagodivediva Acceptable is a stretch

[Waggoner Lab @LabWaggoner]

@biorxivpreprint Identity, ontogeny, and age-related changes in splenic white pulp macrophages in mouse and human spleen
https://t.co/JWJbF6r2fE @Misharin_lab @NorthwesternU

[Peter Sullivan @PeterSullivan4]

Trump budget proposes $5bn cut to NIH

https://t.co/jj20Gyygxd

[Eric Topol @EricTopol]

If FDA does this, which is highly likely succumbing to pressure from RFK Jr, it crosses a new red line and, as far as I know, is unprecedented. Lifting a ban on drugs that are injected into the bloodstream without data for safety or efficacy, so they can be compounded and further promoted to Americans.
@By_CJewett
Gift link
https://t.co/Y1xytcpqDD