A chemistry research team @UQPharmacy engaged in medicinal chemistry, computer-aided drug design, chemical synthesis, nanomedicine, & more. Led by Dr Ben Ross.
Discovery of a brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase published in @CommsBio https://t.co/vyLgzIR3IU - a study led by @nigel_scrutton @UoMMIB & Flaviano Giorgini @uniofleicester with contributions from @RossChemLab@UQPharmacy
Interesting: @nigel_scrutton & colleagues present a brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase, which prevents the accumulation of neurotoxic metabolites. Implications for #Parkinsons?
https://t.co/TECo4FgJPZ
Very pleased to publish a communication about our #prodrug strategy for the brain delivery of small #peptides with neurotherapeutic potential - led by Katalin Prokai-Tatrai and Laszlo Prokai @UNTHSC and Istvan Toth @UQ_SCMB in collaboration with @RossChemLab@UQPharmacy
#mdpipharmaceutics, Brain Delivery of #Thyrotropin-#Releasing Hormone via a Novel Prodrug Approach, https://t.co/dfJZijfZT7
This paper is from Special Issue - https://t.co/AnuMllL030
How do we design better drugs for Alzheimer’s disease? According to a study led by @UQPharmacy researchers, it could be as simple as making a small change to the chemical structure of the current drug rivastigmine. Read more in the journal @CommsChem https://t.co/mDGCZ5Htrh
For a different angle on our study, read Ben's blog post on the Nature Research Chemistry Community "Behind the paper" channel: https://t.co/SNGapkwJMa
How do we design better drugs for Alzheimer’s disease? According to a study led by @UQPharmacy researchers, it could be as simple as making a small change to the chemical structure of the current drug rivastigmine. Read more in the journal @CommsChem https://t.co/mDGCZ5Htrh
Rivastigmine and metabolite analogues with putative Alzheimer’s disease-modifying properties in a C. elegans model (Ross @UQHealth @UQ_News ) https://t.co/KbuwSVqf63
Polyphenolic analogues of the #Alzheimers disease drug #rivastigmine inhibit both #cholinesterase and #amyloid beta fibrillation, and also reveal strategies for the development of #polyphenol-based drugs. Read the story behind our @CommsChem paper here: https://t.co/SNGapkwJMa
A subtle change to the structure of the drug rivastigmine creates inhibitors of both #cholinesterase and #amyloid fibrillation that demonstrate efficacy in vivo in an amyloid beta model of #Alzheimers disease. To find out more, read our @CommsChem article: https://t.co/M1Pp973zj8
Congratulations new @UQPharmacy PhD graduates Dr Suresh Kumar Veliyath and Dr Edward Lee @Eddy_Lee_89 ! It was great to have you as part of the team @RossChemLab - we wish you all the very best for the future 🎓👏🎓👏
Congratulations Dr Edward Lee! Awarded a PhD for your research into antiviral nanoparticles that inhibit both viral entry and viral DNA replication. Read Dr Lee’s @nanoscale_RSC paper https://t.co/50nMmKzYjR and @ACS_Omega paper https://t.co/fawGMnfgGC
Well done Dr Srinivas Kantham and Dr Girdhar Singh Deora @GiriDeora on jointly receiving the @UQPharmacy prize for best HDR student publication in Biomedicinal Discovery and Development! Read their publications in @ACSChemNeurosci https://t.co/N2GD4ak9HA https://t.co/8Bh4Jr0hgb
Congratulations Chau Nguyen on receiving the @UQPharmacy best HDR student publication prize in Biotherapeutic Delivery and Diagnostic Solutions! Read Chau’s article about nanoparticles for targeted drug delivery to the colon https://t.co/wWA0NF5vN3 published in @ACS_AMI
Congratulations Dr Girdhar Singh Deora @GiriDeora on graduating with a PhD in Medicinal Chemistry from @UQPharmacy@RossChemLab ! All the best for your postdoctoral fellowship at @MIPS_Australia - keep in touch!
Loading acyclovir into GAG mimetic-functionalized MSNs creates nanoparticles that target two distinct viral pathways - inhibition of viral entry and DNA replication – read the @ACS_Omega paper https://t.co/FRBxfXXLbJ led by @UQPharmacy@RossChemLab PhD student @Eddy_Lee_89
Our paper led by @UQPharmacy PhD student @GiriDeora on the synthesis and pharmacology of kynurenic acid analogs as prospective multifunctional drugs for #Alzheimers disease is out now in @ACSChemNeurosci https://t.co/ftxaaXctTR
Well done Stephen - Med Chem PhD and a nice Food Chemistry paper (amongst others) https://t.co/wU4Uy7avCR @ELSchemistry @ELSfoodscience. The team @RossChemLab looks forward to celebrating with you at an upcoming graduation ceremony! https://t.co/K2JLIYqTec
Congratulations Dr Stephen Chan! Awarded a PhD in Medicinal Chemistry for your research into polyphenolic food constituents and synthetic analogues as prospective new drugs for #Alzheimers disease. Read about some of Dr Chan's research here: https://t.co/MbA3CybjUK
Congratulations Chau from @RossChemLab - see you at the December Graduation! Read about Chau's research in @ACS_AMI https://t.co/4K6G6M3jP4 https://t.co/IoTq4BZISd