The Weinberg Lab

Computational Physiology Lab. We develop computer models of molecular, cellular, and tissue physiology.

[OSUengineering @OSUengineering]

External funding for research in The Ohio State University College of Engineering is showing no signs of slowing down... $207.49M in FY24, another record high! 📈 https://t.co/voCnnYFRLQ

[Michael Levin @drmichaellevin]

Check out a very cool talk given at our Center today:
https://t.co/t8wTVZGI9s
"Calcium homeostatic feedback control predicts atrial fibrillation initiation, remodeling, and progression" Work of @moise_nick and @SHWeinbergLab

[U.S. National Science Foundation @NSF]

NSF is awarding CyberCorps Scholarship for Service grants to 4 academic institutions with an investment of nearly $15M toward training the next generation of cybersecurity professionals.

Congratulations to @WSU, @IowaStateU, @GeorgeMasonU and @OhioState. https://t.co/0T4NlCnSCW

[AJP-Heart and Circ @ajpheartcirc]

New study provides valuable insights into age-dependent changes in human cardiac gene expression & #electrophysiology, shedding light on molecular mechanisms underlying cardiac maturation and function throughout development. https://t.co/ZDhw7sVilH

@NikkiPosnack @SHWeinbergLab

[CMBE journal @CMBEjournal]

Hirway et al. developed a multicellular computation model to investigate tumor microenvironment remodeling and pre-metastatic niche formation. @OhioStateBME @OSUengineering @SHWeinbergLab

https://t.co/TFEdTEmxrT

[The Weinberg Lab @SHWeinbergLab]

Great thread from @moise_nick on his recent work modeling atrial fibrillation. "AF begets AF" - Nick developed a framework to model this progression from healthy to disease tissue, coupling the electrical activity and substrate remodeling, a complex multi-time scale problem!

[Nick Moise @moise_nick]

Glad to get this preprint out, with @SHWeinbergLab. In atrial fibrillation, chaotic activity directly drives substrate remodeling, which then influences the activity itself. But how does this process evolve long-term, as a coupled dynamical system? 1/13
https://t.co/tzbtvkqh7E

[The Weinberg Lab @SHWeinbergLab]

which informed model predictions of key currents underlying the age-progression of action potential and calcium transient characteristics.

There's a whole lot more to do, and I'm exciting to see where the project will go next.

[The Weinberg Lab @SHWeinbergLab]

We were fortunate to find the perfect collaborator in the Posnack lab at just the right time. Fast-forward to now, and this project has led to an invaluable analysis (and data set) of cardiac gene expression throughout development (> 100 patients, age 5 days to adulthood), ...

[The Weinberg Lab @SHWeinbergLab]

For my group, this project started years ago with the seemingly simple question of – how do we model cardiac electric activity in pediatric heart cells? Which led us to the even more fundamental question of – what do we even know about pediatric heart electric activity?

[The Weinberg Lab @SHWeinbergLab]

Really proud to share this latest work just published in @ajpheartcirc, led by Shatha Salameh, @DevonGuerrelli in the @NikkiPosnack lab and Jacob Miller in my lab.

https://t.co/qODHBGtOEr

[Carol Bradford @CarolBradfordMD]

Congratulations to 3 teams from @ohiostatemed & @osuengineering receiving funding from the Center for Medical and Engineering Innovation to fund cross-college collaborations!
CC: @mnballinger @AleksSkardal @michellenassal @SaurbhRajpal
https://t.co/vJd1TtgQd0

[American Institute of Chemical Engineers (AIChE) @ChEnected]

Umit Ozkan of @OhioState is the 2024 recipient of AIChE's Margaret H. Rousseau Award in recognition of her work bridging heterogeneous #catalysis and #electrocatalysis and for her outstanding work as teacher and mentor. https://t.co/SxHatgOjI1

[Ohio State News @OhioStateNews]

$26M in federal funding announced today will support creation of an @NSF Engineering Research Center at @OhioState to jumpstart natural rubber production in the US & enhance workforce development to fuel the domestic industry. @OSUEngineering @CFAES_OSU https://t.co/ewka998FrU

[OSUengineering @OSUengineering]

In the new Pelotonia Research Center, engineers collaborate with biologists, physicians, data scientists and others to find solutions to daunting health challenges every day: https://t.co/ahye8ivNkK

[Stefano Morotti @MorottiLab]

📢 Postdoc alert!!!

Hey Twitter community,
we are excited to announce two postdoctoral positions available in computational cardiac electrophysiology. Please, help us spread the word by sharing this post!
#Postdoc #Research #CardiacElectrophysiology #ScienceJobs

[Ohio State Research, Innovation and Knowledge @OhioStateERIK]

In Ohio State’s Pelotonia Research Center, Ohio State engineers collaborate with biologists, physicians, data scientists and others to find solutions to some of the biggest health challenges of our time. Meet them here: https://t.co/JqLZ2hnbda

[Kavli Institute for Theoretical Physics @KITP_UCSB]

New KITP Program! #CARDIO26
Multi-Scale Physics of Normal and Diseased Heart: from Ion Channels to Whole Organ

Dates: 3/30/26-4/23/26
https://t.co/jW1giMyHGG

[The Weinberg Lab @SHWeinbergLab]

@OhioStateDHLRI @nih_nhlbi @drMonaElRefaey @OhioStateSurg @OSUWexMed @OhioStateMed Congrats @drMonaElRefaey!

[The Weinberg Lab @SHWeinbergLab]

@HSingh_OSU Congrats Harpreet!

[OhioStateBME @OhioStateBME]

Congrats to Seth Weinberg for being named a Fellow of the @American_Heart Association for his research and contributions in the interdisciplinary field of computational physiology, with focus on cardiac electrophysiology and arrhythmias 🫀

More here: https://t.co/6KjHEn9A60