Sahan B W Liyanagedera

Postdoctoral Researcher in Cell-Free Synthetic Biology

[Filippo Caschera @Stjle]

Synthetic cells for phage therapy: a perspective https://t.co/vhmA6Y0IYA

[Filippo Caschera @Stjle]

Refinement of OnePot PURE and Crude Ribosome Production for Reproducible Cell-free Protein Synthesis

https://t.co/PKKjPovnHG

[Michael Stam @mjstam]

New preprint out!🚨We performed a large scale analysis of physicochemical features extracted from over half a million AlphaFold structural models, and using data-driven methods we showed a link between these features and in vivo behaviour of proteins. Find out more below⬇️1/9

[Martha Clokie @MarthaClokie]

Thanks everyone who came to the enjoyable + thought provoking 13th Oxford Phage Meeting. This was my concluding remarks - showing how the talks mapped to the which phages to use, how many and how will they interact with their environment. https://t.co/W7cEq323X5 #PhgOx23

[Alex Fedorec @ajfedorec]

In the RRI panel, @vdlorenzo_CNB is calling #synbio researchers to move beyond playing around in the lab, produce useful systems that scale, are acceptable and celebrated by society, and are open (i.e. not stuck in IP blackholes) #sbuk2022

[Louise Horsfall @lehorsfall]

@SahanLiyanaged1 presenting how to rapidly engineer phage for targeted therapies. Including a shout out to our sponsors @idtdna #ASBEVI #synbio

[Alevtina @Alevtinita]

Another submitted journal cover I created for my friend's amazing paper (https://t.co/PIpeoZg401). The issue just came out and my image sadly wasn't accepted :(

[Sahan B W Liyanagedera @SLiyanagedera]

@LogarithmicDis @ACSSynBio Thank you @LogarithmicDis! Yes, cell-free is amazing and I hope the methods in the paper make phage engineering in cell-free more accessible to everyone!

[Sahan B W Liyanagedera @SLiyanagedera]

I'm delighted to share the first paper from my PhD published in @ACSSynBio!

SpyPhage: A Cell-Free TXTL Platform for Rapid Engineering of Targeted Phage Therapies.
https://t.co/cGeryYAtmY

#TXTL #phage #phagetherapy #synbio #cellfree

[Sahan B W Liyanagedera @SLiyanagedera]

We describe a scalable method to produce phenotypically distinct phage with the same underlying genotype using Cell-Free TXTL.

Thank you to Joshua Williams in the @antonia_sagona group for his great work on the microscope!

[Sahan B W Liyanagedera @SLiyanagedera]

Check out our @opencovid19 initiative submission to the JOGL platform: https://t.co/QHSdxaZ7pW #JOGL

A Rapid and Scalable #COVID19 detection using advanced pooling and a custom ELISA

#TapestryPooling #MagTRACE. .

[ACS Synthetic Bio @ACSSynBio]

Recoding the phage genome causes its fitness to decrease; is the natural complexity required or is it simply that a satisfactory modular solution has not been found? Read more in ACS Synthetic Biology: https://t.co/wAAOvpnaHI

[Sahan B W Liyanagedera @SLiyanagedera]

@tanvir_h @UKRI_News @STFC_Matters @NERCscience With stats like this, not sure I can afford to take a day off. #ShutDownSTEM

[Tom Ellis @ProfTomEllis]

Building viruses from synthetic DNA shouldn’t be this easy (but it is).