In the absence of trauma, Purtscher-Like retinopathy occurs and is associated with a TON of things but most HY are acute pancreatitis, pancreatic adenocarcinoma, renal 🫘failure, preeclampsia/HELLP Syndrome & 👶🏽 childbirth, and fat embolism syndrome, among others. #eyetwitter
👁️ Ocular signs:
Peau d'orange: diffuse mottling of the RPE
Angioid streaks: brownish gray lines that radiate out from the optic nerve & surround it concentrically
CNV: A major complication of angioid streaks
#meded#medtwitter#eyetwitter#eye#ophtho#ophthotwitter#eyemd
Pseudoxanthoma elasticum (PXE) is a rare genetic disease characterized by elastorrhexia, or progressive calcification & fragmentation, of elastic fibers primarily the dermis of skin, Bruch's membrane of the 👁️, & 🩸blood vessels. Rarely, can cause GI bleeds & 🧠 ischemia. #ophtho
This condition is autosomal recessive and affects the ABC6 🧬 gene, which encodes an ATP-binding cassette transporter protein localized to the mitochondria-associated membrane (MAM).
The average age of onset is 13 years and it is more common in Afrikaners.
#meded#ophtho#eyemd
My attempt at showing you tunica vasculosa lentis (TVL) w a portable 🔬slit lamp in a premature baby in the NICU. TVL is the 🩸vascular network that supplies the 📸 lens during 🤰🏽 fetal development & regresses by term.
It can be persistent, especially in pre-term babies. #ophtho
Rieger anomaly (congenital iris abnormalities eg iris hypoplasia, correctopia & polycoria) associated with systemic findings, such as 🦷 dental, facial 🦴bone defects including maxillary hypoplasia, umbilical abnormalities, or 🧠pituitary involvement is known as Rieger syndrome.
Early on, you can see epi defects & anterior stromal infiltrates. Later signs include the classic ringed stromal infiltrate & radial perineuritis. 🔬 Confocal imaging shows hyper-reflective double walled cysts. Treat with biguanides! #eyes#meded#ophtho#eyetwitter#IDTwitter
🚨🦠 Parasite in the Eye 👁️🚨
Acanthamoeba keratitis is a rare CL associated infection. Found in 💦 pools, 🛁hot tubs, 🚿tap & shower water, & CL solution.
Typical history is pain out of proportion to exam due to its perineuritis.
#parasite#ophtho#eyes#ophthotwitter#meded
Haab striae on retro illumination. Stretching of the cornea in primary 👶🏽 congenital glaucoma = curvilinear breaks in Descemet's membrane. They are typically oriented horizontally or concentric to the limbus #ophtho#eyes#eyetwitter#ophthotwitter#ophthalmology#meded#yo#doc
It is thought to result from an imbalance of angiogenic factors. It can spontaneously regress or resolve with topical steroids. If unresponsive, can try cautery or excision 🔪. #eye#ophtho#ophthotwitter#meded#ophthoed
Conjunctival pyogenic granuloma after pterygium removal. This is a benign vascular lesion that is flesh colored & often pedunculated. It is associated with trauma (surgery), Sturge-Weber, pregnancy, & some meds 💊 (anti-retrovirals, anti-neoplastics, retinoids). #eye#eyetwitter