Vibhu Sahni

[Vibhu Sahni @Sahni_Lab]

Our second paper shows that distinct molecules expressed by distinct corticospinal neuron (CSN) subpopulations direct their axons to appropriate spinal levels: Crim1 regulates thoracolumbar axon extension, while Klhl14 regulates bulbar-cervical extension. https://t.co/1xvIBeyprx

[Vibhu Sahni @Sahni_Lab]

This is the culmination of terrific team-effort by several scientists across continents (some twitterless, but thanks to also @denisjabaudon @jhtsong @CustoGreig)

[Vibhu Sahni @Sahni_Lab]

It’s out! Our first paper shows that CSN axons exhibit targeting specificity in spinal white matter, well before making synaptic connections with spinal circuits. CSN projecting to distinct spinal levels can now be identified molecularly in development. https://t.co/UAIfC7RgPP