saiardi_lab

Interested in everything related to inositol, phosphate, and inositol pyrophosphates from the origin of life to the development of multicellular organisms.

[saiardi_lab @SaiardiLab]

simple, small, and mighty
Human plasma inositol hexakisphosphate (InsP6) phosphatase identified as the Multiple Inositol Polyphosphate Phosphatase 1 (MINPP1) https://t.co/ylLEUBy3dw

[saiardi_lab @SaiardiLab]

The inositol phosphate signalling network in physiology and disease https://t.co/Zbw5sDZugc

[saiardi_lab @SaiardiLab]

The role of inositol in the environmental organic phosphate cycle https://t.co/TGoCmwIJ38

[saiardi_lab @SaiardiLab]

@CellRepMethods great paper

[saiardi_lab @SaiardiLab]

A mammalian model reveals inorganic polyphosphate channeling into the nucleolus and induction of a hyper-condensate state: Cell Reports Methods https://t.co/0oo7ZPXjd2

[saiardi_lab @SaiardiLab]

Congratulation to Tatiana for her nice work.
Phosphate overplus response in Chlamydomonas reinhardtii: Polyphosphat... https://t.co/G51cbeJhHy

[saiardi_lab @SaiardiLab]

On the covalent nature of lysine polyphosphorylation https://t.co/U90m5cUufw

[saiardi_lab @SaiardiLab]

The Ip6k1 and Ip6k2 Kinases Are Critical for Normal Renal... : Journal of the American Society of Nephrology https://t.co/xWMhTzbJqi

[saiardi_lab @SaiardiLab]

Biochemical and structural characterization of an inositol pyrophosphate kinase from a giant virus | The EMBO Journal https://t.co/xdGTw6qeqd

[saiardi_lab @SaiardiLab]

Interesting thoughts are expressed here.

Evolutionary perspective on mammalian inorganic polyphosphate (polyP) biology https://t.co/Dkjf4RGquR

[saiardi_lab @SaiardiLab]

Check how redox signaling regulates PP-IPs levels.
β-lapachone regulates mammalian inositol pyrophosphate levels in an NQO1- and oxygen-dependent manner | PNAS https://t.co/M7lFit6scX

[saiardi_lab @SaiardiLab]

Inositol pyrophosphate profiling reveals regulatory roles of IP6K2-dependent enhanced IP7 metabolism in the enteric nervous system https://t.co/Uobg5Sma8U
Fantastic work by Masatoshi Ito and collegues. The uniqueness of intestinal PP-IPs metabolism is an exciting discovery.

[saiardi_lab @SaiardiLab]

HIV-1 needs the cell metabolite IP6 to build its capsid and infect cells https://t.co/mnGqjW0QCP

Another fantastic work by Leo and his collaborators

[saiardi_lab @SaiardiLab]

Regulations of myo-inositol homeostasis: Mechanisms, implications, and... https://t.co/5e2fLC3dvZ

[saiardi_lab @SaiardiLab]

Great work by Masatoshi Ito and colleagues
Inositol pyrophosphate profiling reveals regulatory roles of IP6K2-dependent enhanced IP7 metabolism in enteric nervous system https://t.co/xLjPIyqop0

[bioRxiv @biorxivpreprint]

Inositol pyrophosphate profiling reveals regulatory roles of IP6K2-dependent enhanced IP7 metabolism in enteric nervous system https://t.co/i1ajrw2uWS #bioRxiv

[saiardi_lab @SaiardiLab]

An exciting work liking inositol pyrophosphate to kinetochore functions
Inositol Pyrophosphate-Controlled Kinetochore Architecture and Mitotic Entry in S. pombe https://t.co/WyewTgNprE #mdpijof via @JoF_MDPI

[saiardi_lab @SaiardiLab]

Congratulation to Minh and all the other co-authors for revealing an inositol phosphate unexplored (until Minh work) pathway.
Stable isotopomers of myo-inositol to uncover the complex MINPP1-dependent inositol phosphate network https://t.co/BLOMsYnrT2

[BRIC-NABI @NABI_India]

New Publication: Congratulations to the authors. This work identified role of plant Inositol Pyrophosphate Kinase (VIH) in modulating the expression of cell-wall homeostasis genes, and tolerance to water-deficit stress.@DBTIndia @BMCBiology
https://t.co/WuNb06NPXZ

[saiardi_lab @SaiardiLab]

Polyphosphate degradation by Nudt3-Zn2+ mediates oxidative stress response https://t.co/5lHXEgtY8A