Is the apicoplast essential for Toxoplasma persistence? Sometimes you have to go through rather convoluted ways to answer a simple question. Huge effort of PhD student @SanchezSyrian in collaboration with the lab of Nico Blanchard @InfinityTLS to find out:
https://t.co/Vc3rxJfPdS
How does Toxoplasma gondii tachyzoites multiply so efficiently?
Our review dives into the molecular choreography of endodyogeny—scaffolds, transcription factors, and cytoskeleton that enable parasite division.
👉 https://t.co/Xc642un7gY
@be_maanasa@VMudiyam@TrendsParasitol
I finally found the time to write a short piece on ATG8ylation of the apicoplast. You may want to check it out here: https://t.co/hAJzfetujR
#autophagy#ATG8ylation#apicoplast
🚨New paper out! 🚨
The apicoplast is an essential plastid retaining many crucial metabolic pathways 🦠🏭 However, bypassing all of them makes the apicoplast dispensable!
https://t.co/ELkGjzaE2Q
Thrilled that @MBoCjournal chose our picture for their March issue cover, always happy when Toxoplasma gets the spotlight! Thanks to the Editors and check out our paper on methylglyoxal metabolism in the apicoplast here: https://t.co/EMh3wwGzYc
Stoked to see the latest research from our lab now out in @PLOSBiology! Check it out to learn more about lineage-specific adaptations in the cytosolic iron-sulfur assembly pathway in Apicomplexa. #ironsulfur#apicomplexa
https://t.co/nHHxt2br16
Excited to see our paper published in MBOC! 🎉 Our research explores a glyoxalase-like protein in the apicoplast, crucial for Toxoplasma growth and organelle homeostasis maintenance. Huge thanks to the newly promoted Research Director @s_besteiro🏋♂️
https://t.co/mQPvz6JTru
Delighted to share our study on a major Toxoplasma virulence factor that prevents lytic host cell death.
Many thanks to @ParaFrap for support, constructive reviews and all labs involved: Melissa Lodoen, Hiba El Hajj, @MGissot, @KarineLeRoch1
Link : https://t.co/vQvOjAYJOU
You want to know more about iron-sulfur cluster biogenesis in Apicomplexa? Have a look at our latest review, just out in the "Biogenesis and function of FeS proteins" special issue of @BBAjournals BBA Mol Cell Research:
https://t.co/bxFVzCLDKp
Extremely proud to see this beautiful collaboration with @yiweichang lab published. Thanks to all the people involved in this work. #ExM#CryoET
https://t.co/JbKXswAcqd
Years of hard work but is it now officially online. Thank you to my amazing students and collaborators for this great story! A kalihinol analog disrupts apicoplast function and vesicular trafficking in P. falciparum malaria | Science https://t.co/JIVF5wKlGY
#Apicomplexans need specialized structures to invade host cells & replicate. @petersmback@GEWard14 @ToxInLA &co show that alveolin protein IMC6 is crucial for maintaining cellular morphology, invasion & successful replication in #Toxoplasma#PLOSBiology https://t.co/29aOoagoQ8
A new study in @PLOSBiology from our lab shows the role of the PP1 phosphatase in controlling the tachyzoite cell cycle and amylopectin storage in T. gondii. Kudos to the two PhD students involved: AS Khelifa and @be_maanasa !
#PLOSBiology: https://t.co/BaGpbEzNxY
Postdoc position available to work with me, in collaboration with Chris Lane @LaneLabURI, on Nephromyces, the closest non-parasitic, extracellular symbiont relatives of the blood parasites (Plasmodium et al). How did the business of blood parasitism start?
https://t.co/F34tr93d2Y
Congrats to @SanchezSyrian and all the authors involved in the paper describing a novel protein involved in apicoplast homeostasis and parasite growth! 👏🦠🐈⬛
https://t.co/L79iKejGBY
Excited to share a new preprint investigating the importance of the mitochondrial transporter ABCB7 for iron-sulfur cluster biogenesis in Toxoplasma. Great collaboration with @s_besteiro
https://t.co/IalKbkZuAB