The essential host genome for Cryptosporidium intracellular survival exposes metabolic dependencies that can be leveraged for treatment (full thread in that other place!) @ghostpathogen
https://t.co/HPgchtfdHs
Targeted CRISPR Screens Reveal Genes Essential for Cryptosporidium Survival in the Host Intestine (full thread in the other place!) @_Lucy_Watson
https://t.co/E8vuD6sDkV
📢 Hiring a research technician! Interested in parasite biology? Fancy gaining expertise in messing with genes in malaria parasites?
Then apply! https://t.co/oVwF6vX19l
(everyone else, pls help out a guy and RT 🙏)
A TL;DR below 👇DM/email me for enquiries
APPLY!!! Combined with expansion microscopy you will be able to achieve high resolution images even with optical wide microscopy. And if you need a #U_ExM protocol or help DM me.
This threatens the ability of researchers around the world to battle important diseases. Malaria, chagas, cryptosporidiosis, and leishmaniasis are just a few of those affected. Why is #NIAID choosing to obstruct its own research goals despite unanimous opposition from scientists?
Cryptosporidium parvum is a parasite that causes a diarrheal disease called Cryptosporidiosis (also called “Crypto”). It is found worldwide and typically infects the small intestine of humans and animals. Any dog, cat, farm animal or wild animal, including birds, fish, and reptiles, can become infected, though calves are the most likely animal to be infected. Anyone can get cryptosporidiosis, but it is more common in persons who are under two years of age, travel, work with animals, or are in close personal contact with someone who has this disease. Learn more about Cryptosporidium parvum beginning on page 123 of Parasitic Diseases, Seventh Edition. Download today at https://t.co/fb1n3eQpFj
Read our new paper: Cryptosporidium impacts epithelial turnover and is resistant to induced death of the host cell by @BethanWallbank out today in @mbiojournal. Great team effort with @RyanPardy2@KingOfPathogens@BrodskyIgor https://t.co/IPueHfD54G Infected = not apoptotic:
My first-author work on the Cryptosporidium single-cell atlas and sex determination is online @Nature!!! In @striepenlab we sequenced the transcriptomes of over 9000 parasites showing a direct commitment to sexual development! https://t.co/elu8F7Wai7