ACR/EULAR Criteria for Rheumatoid Arthritis
A score of ≥6/10 supports rheumatoid arthritis classification, but only after true clinical synovitis is present and better explanations have been excluded & an important point: a score below 6 does not always rule out early RA.
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Methotrexate lowers folic acid levels in your body, which can lead to side effects like mouth sores, stomach upset, and abnormal liver tests, so doctors often recommend taking folic acid supplements alongside it to help prevent these problems.
Taking folic acid with methotrexate doesn’t reduce the medication’s effectiveness for conditions like rheumatoid arthritis, but it does make it easier to tolerate by cutting down on side effects.