Savi Adikari

Consultant in Sexual Health & HIV

[NHS England @NHSEngland]

The NHS has published single-sex guidance for staff and patients.

Read the guidance on NHS staff facilities here ➡️ https://t.co/cpf1F69ODv

Read the guidance on hospital accommodation for patients here ➡️ https://t.co/UVYqlJ0pEh

[BBC News (UK) @BBCNews]

GP says she was forced out of job after raising concerns about gender treatment https://t.co/ieNxfP5OIr

[Dr. Jason Fung @drjasonfung]

Fasting and Heart Disease - hardly. https://t.co/u2Nv8zc9WA

[IAS - the International AIDS Society @iasociety]

In a proof of concept, @UvA_Amsterdam "scientists say they have successfully eliminated #HIV from infected cells, using Nobel Prize-winning Crispr gene-editing technology". https://t.co/bzzWR2uTgg

[Savi Adikari @SaviAdikari]

Read this @Doctors_net_uk news story: Researchers say HIV can be eliminated from cells using gene editing tool https://t.co/fCJLQYEec8

[Nick Norwitz MD PhD @nicknorwitz]

8 hour time-restricted eating linked to 91% higher risk of cardiovascular death? 🫀

Really?! Not so "fast" ...🤔

Upon popular request, I'm covering this news release.

👉 1) This is not in reference to a published paper.

Rather, these were "preliminary" results presented at an AHA epidemiology conference. The paper that these data may yield is not published, so informed commentary is necessarily limited.

👉2) The article notes, "Previous research has found that time-restricted eating improves several cardiometabolic health measures, such as blood pressure, blood glucose and cholesterol levels." They also provide no biologically plausible rationale for the results.

👉3A) The results themselves were based on self-report...

This doesn't invalidate the data itself (I'm not against questionnaires); however, in the context of findings that are at odds with other data (as noted above) and absence of presented biological plausibility, and high probability of reporter bias (e.g. perhaps people with higher risk factors and more clinical clinical 'concern' are more likely to report trying 16-8), I would take this with a grain of salt (but not too many grains... because that will raise your blood pressure... with TRF helps, btw).

3B) "Time-restricted eating was determined on the basis of just two days of dietary intake”

3C) Also "the nutrient quality" was not assessed

4) Not all elements of the news coverage were clear/consistent. E.g. "Among people with existing cardiovascular disease, an eating duration of no less than 8 but less than 10 hours per day was also associated with a 66% higher risk of death from heart disease or stroke." Is this saying in those with CVD <8 was okay, but <10 was bad? That's odd and a little "sus" (as the kids say)

And, in closing, it's worth noting the news article itself says "The Association makes no representation or guarantee as to their [the data's] accuracy or reliability."

I'll continue to skip breakfast as it suits me.

You do you.

cc' @MatthewNehsMD @ChrisPalmerMD @drjasonfung @bigfatsurprise @DoctorTro @KenDBerryMD @AdrianSotoMota anything to add?

You gonna' pick up some Cheerios for your heart?

[Nina Teicholz, PhD @bigfatsurprise]

Intermittent fasting is linked to a 91% increase in heart attacks? Weak epidemiological data. Based on a press release only, no way to check this data.
The American Heart Association should not be press-releasing a mere abstract. And a bunch of other arguments summarized well here:
https://t.co/tm5Rqk6lTx

[Justin Trudeau @JustinTrudeau]

The news coming out of the United States is horrific. My heart goes out to the millions of American women who are now set to lose their legal right to an abortion. I can’t imagine the fear and anger you are feeling right now.

[richard horton @richardhorton1]

Here is the full abstract of the interim phase III results of the Oxford/AstraZeneca COVID-19 vaccine—the paper is fully and freely available on our website. These results are truly a landmark.

[The BMJ @bmj_latest]

Since the emergence of SARS-CoV-2, there has been an unparalleled global effort to characterise the virus and the clinical course of disease. What do we know about the pathophysiology of the virus so far?
https://t.co/fEoVfu0rrB

[The BMJ @bmj_latest]

The pandemic is at a critical juncture, and airborne transmission of covid-19 is now the plausible cause of a few superspreading events. These strong signals should not be ignored by politicians and public health leaders, argues this Editorial
https://t.co/pydJczwZhH

[BHIVA @BritishHIVAssoc]

Don't forget to register for this webinar on the HIV haematological malignancies from @TheLancetHIV and @TheLancetHaem #HIV #lymphomas #HIV

[BHIVA @BritishHIVAssoc]

- People with HIV should follow government guidelines on social distancing, hand washing and face coverings
- anyone with a detectable viral load, CD4 count less than 200, particularly people with advanced HIV (CD4 &lt;50), should be cautious and minimise risk of exposure

[Diarmuid Nugent @diarmuid_nugent]

Perhaps not the first infectious condition on everyone's mind right now... but I'm very pleased to see our IUSTI-Europe guidelines for the management of anogenital warts published in @TheJEADV ! They are free and open access via this link:

https://t.co/HQlzyAyezJ

@BASHH_UK

[Doctors’ Association UK @TheDA_UK]

HCW will rally over equal pay, unsafe staffing levels and the privatisation of the NHS.

"Please, stand with us. Change can happen, but we need our collective voices to be heard. We need to be loud and we need your voice." #EqualPay #GlasgowGreen

https://t.co/WDHkjSKUqR

[Prof Yvonne Gilleece @ProfYGilleece]

Great article includes references to &amp; quotes from ⁦@SWIFT_women⁩ ‘s ⁦amazing @crageshri⁩ and brilliant Vanessa Apea. If this resonates check out our webcast on Race, Equality &amp; Health Outcomes on ⁦our website https://t.co/gXKKfnud2E https://t.co/sddO4TgTwq

[Prof Jackie Cassell @jackiecassell]

We are looking for new examiners for the Diploma in Genitourinary Medicine (formerly Venereology). Best exam, best venue, best speciality. Look out for @BASHH_UK communications in next few days!@ApothecariesLDN

[The BMJ @bmj_latest]

"Improving what people eat has huge scope for improving physical and mental well being and taking pressure off health systems. Reducing the effects of a second wave of covid-19 is just the latest most urgent reason." @fgodlee in our latest Editor's Choice
https://t.co/loL0rGeWMI

[BHIVA @BritishHIVAssoc]

You may have heard of the case announced at #AIDS2020 of a Brazilian man in long-term remission from #HIV.
Here are some key facts.
Remember, although this news is promising, we do not recommend treatment breaks or the use of nicotinamide as an adjunctive HIV treatment.

[Paul Sax @PaulSaxMD]

It might seem hard to believe, but there was an International AIDS Conference last week, #AIDS2020. Yep.
Here's a Really Rapid Review of some highlights -- what did I miss?
https://t.co/RY39C4jdNW