I find it hard to believe that all the old villains we’ve seen so far won’t return (like Kado Thorne even after his supposed death, Megalodon, etc.). Geno is holding something extremely big, and The Nothing is simply watching before screwing over its own Last Reality.
Believe me, a collaboration between The Last Reality and Geno is absolutely impossible. Geno is an incredibly powerful and intelligent man. He exploits other people’s technology to reach his goals. He COPIES, but he does not collaborate. THE NOTHING has NOTHING to do with GENO.
Take this as a prediction: The Last Reality is going to kick Geno’s ass far more than you think. Voyager will play a role in this, and for the first time the Seven will probably deal with the Cube Queen without fighting. In short, multiple factions against Geno.