With @Sean_SJ_Huh (our recent PhD!) and @GeorgeJSaunders we deployed the rarely used Cornforth rearrangement to remove an atom from a macrocycle. This @angew_chem paper studies the interplay between reactivity and uncommon conformational states.
https://t.co/8PdZikSMXF
This #AsianHeritageMonth , may we raise our voices, stand together to #FaceRace, and fight racism in all its forms, wherever it exists – today and every day, into a more inclusive future. Watch this incredible video from @melissagrelo & @LaineyGossip.
Here we look at how 2D events result in interesting 3D outcomes.
Boulton-Katritzky rearrangement enables this in macrocycles. Grateful to Shinya Kobori (now back in Japan at Nippon Soda), @Sean_SJ_Huh, and Solomon Appavoo for their hard work.
@J_A_C_S
https://t.co/QrW2YI2MUD
Together with my students Sean Huh and Solomon Appavoo, we evaluate the role of amidines on the conformation of cyclic peptides. It is a marvellous functionality: isosteric with amides, but way off in terms of pKa. https://t.co/OoFtz4TjWO
When applying as a grad student, we never think about our race, our gender, or our sexuality. We think about how we can be scientists. Essays like these expose ourselves to the label people subscribe to us making us lose focus and even doubt our inclusion in the science community