Sebastian Brandner

[Sebastian Brandner @Seb_Brandner]

@nancyk121 Yes, I spent 2years in Neurosurgery where I learned craniotomies and importantly discovered my passion for neuropathology 🔬

[PabloGarciaReitboeck @pablogarciareit]

@AlexFellows1 @DervisSalih1 Beautiful!

[Sebastian Brandner @Seb_Brandner]

Discovery of drug response in IDH mutant gliomas with a potential to treat astrocytomas and oligodendrogliomas.
https://t.co/azSBg5XEMP
Very pleased that this has just been published in CANCER RESEARCH. Will be in Pubmed soon.

[Sebastian Brandner @Seb_Brandner]

Mutant IDH sensitizes gliomas to endoplasmic reticulum stress and triggers apoptosis by MicroRNA183-mediated inhibition of Semaphorin 3E https://t.co/wdUJKAJgsZ

[Sebastian Brandner @Seb_Brandner]

Methylation array profiling of adult brain tumours: diagnostic outcomes in a large, single centre https://t.co/h9yG3kqeay

[Sebastian Brandner @Seb_Brandner]

I think it may be more common than previously thought. Just need to observe carefully and connect the facts.

[Sebastian Brandner @Seb_Brandner]

Indeed, important and groundbreaking finding that change the view on transmissible proteopathies

[Gargi Banerjee @DrGargiBanerjee]

Zane Jaunmuktane speaking now about abeta transmissibility - one of the most exciting new observations in CAA in recent years #ICAA18 @UCLBrainScience

[Sebastian Brandner @Seb_Brandner]

https://t.co/yzQWDRQysI Inhibition of GPR158 by microRNA-449a suppresses neural lineage of glioma stem/progenitor cells and correlates with higher glioma grades

[Sebastian Brandner @Seb_Brandner]

https://t.co/JWdj7bg3WY: GPR 158 and miR-449 as new brain tumour malignancy bio-markers and possible therapeutic targets

[Sebastian Brandner @Seb_Brandner]

It was an interesting and engaging event. Well done! https://t.co/eXkc8DtwOZ

[Vincent Clay @mtvc2]

Testing our histological diagnosis skills with @Seb_Brandner at @EU_Brain #BrainMissionFP9

[Sebastian Brandner @Seb_Brandner]

https://t.co/yzQWDRQysI Inhibition of GPR158 by microRNA-449a suppresses neural lineage of glioma stem/progenitor cells and correlates with higher glioma grades: Possible new therapeutic target and biomarker.

[DTHSTR @CDADeathStar]

Inhibition of GPR158 by microRNA449a suppresses neural lineage of glioma stemprogenitor null https://t.co/O7sPBemjlO #DTHSTR

[Tony Avril @avril_tony]

#stem_cells_GBM_papers / #miRNA_GBM_papers:
Inhibition of GPR158 by microRNA-449a suppresses neural lineage of glioma stem/progenitor cells and correlates with higher glioma grades
Oncogene 2018
https://t.co/pAt6CAvDS1

[NeuroStemCells @NeuroStemCell]

Inhibition of GPR158 by microRNA-449a suppresses neural lineage of glioma stem/progenitor cells and correlates with higher glioma grades. https://t.co/V2qBl86pSC #Neuralstemcells

[Sebastian Brandner @Seb_Brandner]

Next step: to update with new subclasses. https://t.co/joOIdAHVfW

[Sebastian Brandner @Seb_Brandner]

We are not changing that much actually. Of 400 tumours in our lab, we changed diagnosis on 20%. And these 400 are a 10% selection already. So, no worries we'll stick with WHO 2016 for most tumours for a while https://t.co/mINRPXrjEM

[Sebastian Brandner @Seb_Brandner]

@DrPaolini @DrMMB @thebigcobb @sam_albadri @neuropathology @MelanieBoisMD @ActaNeuropathol They look beautiful. But rarely done. Even in large centres.

[Sebastian Brandner @Seb_Brandner]

@chromosomeOMICS @NatureGenet Yes, usually works on FFPE. we have done 400 in the last 2 years!

[Sebastian Brandner @Seb_Brandner]

and we thought: let's look into this in more detail. https://t.co/a3yPKLqnnh

[Sebastian Brandner @Seb_Brandner]

then we saw this
https://t.co/0lJ2iXwYxH