Sewald Lab

We are an interdisciplinary research group @unibielefeld working on the interface of synthetic chemistry and biochemistry. Student managed account.

[Sewald Lab @Sewald_group]

We are pleased to announce the publication of our newest work on highly cytotoxic cryptophycins in @angew_chem ! A lot of synthetic work @unibielefeld together with valuable crystallographic insights from close collaborators Dr. A. E. Prota and Dr. A.-C. Abel @psich_en #antitumor

[Angewandte Chemie @angew_chem]

Highly Cytotoxic Cryptophycin Derivatives with Modification in Unit D for Conjugation (Norbert Sewald and co-workers) @Sewald_group @unibielefeld @voss_jona #openaccess 🔓 https://t.co/gNWgS6Ytxd

[Sewald Lab @Sewald_group]

Thrilled to share Nicolai's @NMontua concept paper on the symbiosis of biocatalytic halogenation with metal catalysis published in @ChemBioChem! Check it out here: https://t.co/axiM34G3xB @unibielefeld

[Chemistry Europe @ChemEurope]

#ChemBioChem Perfect Partners: Biocatalytic Halogenation and Metal Catalysis for Protein Bioconjugation (Norbert Sewald and co-workers) @Sewald_group, @unibielefeld #openaccess https://t.co/fxMO1yXNB1

[Catalysts MDPI @Catalysts_MDPI]

Two Novel, #Flavin-Dependent #Halogenases from the #Bacterial #Consortia of Botryococcus braunii #Catalyze Mono- and #Dibromination

📝 by Pia R. Neubauer, Olga Blifernez-Klassen, et al.@CeBiTec

👉https://t.co/NlgWhfSEkV

[Magicbullet::Reloaded @MagicbulletR]

We are looking for applications from talented young researchers for 15 PhD positions in anticancer drug development and delivery in Finland, Germany, Hungary, Italy, Switzerland, and the UK! Please check https://t.co/uOs9iokvt4

#MSCAjobalert #H2020 #MSCA @MSCActions @EU_H2020

[Sewald Lab @Sewald_group]

@VWendisch @CeBiTec @unibielefeld @csir_niist Congratulations!

[ChemBioChem @ChemBioChem]

Special Issue on "The 10th International Peptide Symposium (IPS)" that took place in Kyoto last December (https://t.co/OIogNh82IT), guest-edited by Shiroh Futaki, Katsumi Matsuzaki (@KyotoU_News), and Yuki Goto (@UTokyo_News_en). Thanks to @EJPLab for the amazing front cover!

[ACS Publications Bio & Med Chem Content @ACSBioMed]

"Side chain-to-tail cyclized RGD peptides exhibit distinct geometries that allow modulation of affinity," Isabell Kemker @unibielefeld https://t.co/WFlvhh8EFy

[Sewald Lab @Sewald_group]

Now online - our latest paper on side chain-to-tail-cyclized RGD peptides combining enzymatic halogenation and cross-coupling to modulate integrin affinity.
https://t.co/cOWI9RsNOh

[Turner Biocatalysis @Turner_Biocat]

We're hiring for a post-doc in computational chemistry/biochemistry to work with @nigel_scrutton and @AstraZeneca. Experience with Rosetta very desirable!
https://t.co/99e5a54bOh
#biocatalysis #postdoc #job

[Sewald Lab @Sewald_group]

YaBiNaPA - research_tv Universität Bielefeld https://t.co/9jemZiR7Fn via @YouTube

[Sewald Lab @Sewald_group]

If you are interested in natural product discovery, check our recent film on German–Cameroonian graduate school @YaBiNaPA !

[Bielefeld University @unibielefeld]

How can the medicinal plants used in traditional African medicine be used to produce low-cost drugs? That is the goal of the German–Cameroonian graduate school @YaBiNaPA. https://t.co/sNIulWIj1e

[Sewald Lab @Sewald_group]

Fabulous start of Biotrans 2019 in Groningen! Looking forward to an inspiring conference on the inspiring world of enzymes!

[Grossmann Lab @TomNGrossmann]

First a great talk by Norbert @Sewald_group @UvA_Amsterdam and now visiting the old lab buildings of van ‘t Hoff and van der Waals with Jan v. Maarseveen and Marcel @M_S_8_8

[Sewald Lab @Sewald_group]

Targeted drug delivery applying RGD-cryptophycin conjugates - our latest paper is available in @ChemistryOpen . @ETN_Magicbullet
https://t.co/EQP1gIAKRN

[Bielefeld University @unibielefeld]

Ein Symposium an der @unibielefeld rund um #lifescience – für Studierende von Studierenden. Ein Interview zur Tagung vom 28. bis 30. Juni mit Charlotte Mann, Bielefelder Stadtgruppensprecherin der Junior-Gesellschaft für Biochemie und Molekularbiologie. https://t.co/G4OmerHUGz

[Pharmaceutics MDPI @MDPIpharma]

#mdpipharmaceutics, New paper!

Octreotide Conjugates for #Tumor #Targeting and #Imaging, https://t.co/Xmz5EuNsq2

Welcome to read!

[Sewald Lab @Sewald_group]

Conjugation of the cytotoxic depsipeptide cryptophycin to octreotide allows for specific tumor targeting - our paper on synthesis and biological study of octreotide conjugates is now online in @MDPIpharma @ETN_Magicbullet

https://t.co/tbMDewsYMJ

[Sewald Lab @Sewald_group]

Our recent paper on synthesis and biological evaluation of RGD-cryptophycin conjugates in collaboration with @ETN_Magicbullet has been released in @MDPIpharma.
Full text available: https://t.co/mcuFtWx2Vz

[Chris Nawrat @BRSM_blog]

I had a request for this, so here it is #GreenChemistry #ACSOrlando

[Sewald Lab @Sewald_group]

Heck cross-coupling succeeds in water using unprotected bromotryptophan as a substrate. Our recent paper is now online in @ChemEurJ.
https://t.co/XFtnaO9kCc