Shantanu Pendse

MedOnc

[decodingmyroots.com - नित्यकर्म सर्वोपरि @MonaADhar]

Kashmiri women are known for their long, elegant earrings, a symbol of grace and culture.

But in the 1998 Wandhama massacre, where 23 Kashmiri Pandits were killed, even this symbol was violated.

When the bodies were found, women’s ears had been cut off, not by terrorists alone, but by locals who tried to loot jewelry and chose mutilation when removal took time.

This is the brutal truth behind the romanticised idea of Kashmiriyat.

It is a reminder of the betrayal, dehumanisation, and silence faced by Kashmiri Pandits.

History must be remembered.
Forgetting is injustice.

[Shantanu Pendse @ShantanuPOnco]

@ranaprshnt @volklub Any tricks /tips to get this mileage ?

[Kaal Chiron काल्किरण @Kal_Chiron]

Anant Kanhere, who sacrificed his life for the motherland at the age of 18!

A young man from Konkan goes to Sambhajinagar (Aurangabad) for secondary education, takes part in revolutionary work there, gets a pistol sent by Mr. Savarkar from London and kills a treacherous and high-ranking Englishman, all of it is extraordinary and impossible! But the name of the young man who made this impossible act possible was Anant Laxman Kanhere!

Anantrao was born in 1891 in the village of Ayni-Mete in Ratnagiri district. He went to Aurangabad to study English with his maternal uncle. After a few years, he started living in a rented room with Gangaram Marwadi. Kashinath Tonpe of the freedom fighter secret society of Nashik gave Gangaram and Anantrao the oath of the secret society. After Madanlal Dhingra's revenge against Curzon Wylie, Anantrao also became impatient with such an act. Then Gangaram tested Anantrao by placing hot iron tongs on his hands and asking him to hold the hot glass of a lit chimney with both hands. Despite lighting both lamps, Anantrao's posture was unwavering!

Around this time, a cruel and hypocritical officer named Jackson was the District Collector of Nashik. He had imprisoned true lawyers, kirtan singer Tambe Shastri, Babarao Savarkar and other patriots. Jackson wrote his obituary for many such misdeeds. It was this fate that chose Anantrao. Anantrao practiced pistol shooting to kill Jackson. He went to the District Collector's office and looked at Jackson carefully. 'If Jackson is killed and has to be hanged, at least his parents should have a photograph of him as a memento'; so he also took a photograph of himself.

On December 21, 1909, a rehearsal of the play 'Sharda' by the Kirloskar Natak Mandali was organized in the Vijayanand Theatre of Nashik in honor of Jackson. As Jackson was entering the theatre through the door, Anantrao, who had already arrived, fired a shot at Jackson. It went through his armpit. Anantrao, acting quickly, fired four shots at Jackson from the front. Jackson collapsed on the spot. Anantrao calmly surrendered to the guards.

Anantrao and his associates Anna Karve and Vinayak Deshpande were sentenced to death on the charge of murdering Jackson. On April 19, 1910, these three revolutionaries were hanged at 7 am in Thane jail with a courageous attitude. Despite the request of their relatives, the British government cremated the bodies of all three on the banks of the Thane creek and threw their ashes into the creek so that no one would get them.

We are free today because of the sacrifices of many like martyr Anant Kanhere, who sacrificed his life for the country at the age of 18.

[Shantanu Pendse @ShantanuPOnco]

@DrRishabhOnco Other wat round, have seen irAEs suddenly coming up post RT in otherwise well-going pts from tox persp

[Shantanu Pendse @ShantanuPOnco]

Very well written and absolutely agree to thi Dr. @kartik . Failure of drug straight away leads to diease progression in cancer. No way to know what actually happened !

[Karthik Balachandran @karthik2k2]

For hypoparathyroidism, we give a drug called calcitriol which helps in calcium absorption. The innovator brand costs ₹ 23 per tablet. The Jan Aushadi generic costs ₹ 21 per strip of 10 tablets. That’s a 10 x price difference.

Yet, in my experience, the Jan Aushadi drug works almost as well as the original brand. I have checked it with serum calcium , urine calcium creatinine ratio and not just subjective symptoms.

On the other hand, during residency, we had some patients taking 350 - 400 mcg of thyroxin ( >5 mcg/kg /day). They used to say they are uneasy with commercial tablets and that’s why they preferred government supply. They used to say “Set aagala sir”- meaning it didn’t suit them, but they couldn’t tell why. When we shifted them to branded drug, they developed thyrotoxicosis with less than half the dose they were taking ! Which means that the generic tablet had er.. “quality issues”.

This is the problem with generic drugs - you can’t really be sure. It’s a hit and a miss. In both cases we had a way to check if the drug worked. So we could adjust accordingly. Similarly if the drug didn’t work, it would just result in tiredness or cramps - nothing life threatening.

Now imagine if it were blood pressure drugs or worse cancer drugs. If the drug doesn’t work, the consequences can be disastrous and we may not be able to detect until it’s too late. The worst part is published studies on innovator vs branded generic vs pure generic are not that common and test a small slice of drugs. The results of these studies directly contradict most doctors’ and patients’ lived experience.

Where there’s a discrepancy between the map and the terrain, we trust the terrain. Same is the case with generics and published studies.

[Shantanu Pendse @ShantanuPOnco]

@karthik2k2 @tamilravi Absoutely agree to this. Everyone has this basic right to make his/her own choice.

[Anirban Maitra @Aiims1742]

Funny how two of the more interesting pieces of data at #ASCO25 have little to do with extraneous medications per se, but rather the body’s circadian rhythm and physiology:
1: Exercise after surgery
2: Checkpoint inhibitors in the morning

[Dr Kunal Jobanputra MD, DM @KNJobanputra]

When it raises more questions than answers. Billions of dollars going into ctDNA #ASCO2025
Usage should be restricted to specific clinical circumstances.

[Dr Poornima 🇮🇳 @PoornimaNimo]

One community does not forgive the Hindus of India for demolishing one mosque in Ayodhya.

Hindu women forgive even the k*llers of their father and husband and sing songs of secularism.

Nobody can wake the sleeping secular Hindus.

[Shantanu Pendse @ShantanuPOnco]

@iamThe_Surgeon Best wishes Kunal.

[Dr. Datta M.D. (Radiology) ✈️ Switzerland @AI4Good @DrDatta_AIIMS]

❤️In the heart of Kolkata, seven doctors sit quietly on the frontlines of a battle, not with stethoscopes, but with empty stomachs.

🚨Some haven’t eaten in over 14 days, many for 8 days, others for 5!

🚨They’re fighting for justice, for dignity, for every doctor who feels unheard in this broken system. Each day of their hunger strike is a plea that echoes across the silence of those in power.

🫡These are not just doctors—they are heroes, sacrificing themselves for a cause that affects us all.

🆘Will you stand with them?

[Mr Sinha @Mrsinha]

This is not Lebanon, Iran, Pakistan or Bangladesh but Kashmir (India). They’re protesting against the kiIIing of #Hezbollah terrorist #HassanNasrallah.

It seems Stone pelting has stopped because of the fear of pallet guns but mentality is still same ; pro terrorism… Ticking TimeBombs…

[True Indology @TrueIndology]

Gorakhnath temple has a recorded history of at least 800 years.

The temple existed even before Nawab Asaf-Ud-Daulah was born in 18th century.

How could the Nawab grant land for construction of a temple that existed for hundreds of years before his own birth?

Fake news!

[Radharamn Das राधारमण दास @RadharamnDas]

I ate the sacred #TirupatiLaddu,

Millions of Hindus have, just like you.

But today, our faith they defiled,

Feeding our Bhagavan what’s unholy and vile.

Beef fat in the Laddu—a sin so deep,

A betrayal that makes our hearts weep.

For the love of Dharma, for our sacred right,
A massive protest must rise, a righteous fight.

Hindus, awaken! Let your voices soar,
This insult we can’t take anymore.
The time has come, no more delay—
#FreeHinduTemples without further sway!

#Tirupati #TirupatiLaddu

[Ganesh @me_ganesh14]

Resident Doctors are real heroes. They pre-empted the PR game of #MamataBanerjee and put her back foot by asking for live streaming. They know that Mamata Banerjee wants to play the politics of maligning doctors. Good going. Hitler Didi needs to be defeated like this.

[Shantanu Pendse @ShantanuPOnco]

@angryoldman27 True..this sadistic outlook needs to change first ..1.most of the chemos are covered under govt schemes these days. 2. PET is not really required for every patient. 3. Book costs lesser than most of the smart phones residents / doctors buy.

[Shantanu Pendse @ShantanuPOnco]

Absolutely ..must end

[ADV. ASHUTOSH J. DUBEY 🇮🇳 @AdvAshutoshBJP]

VIP CULTURE SHOULD BE BAN: This is how normal people are treated in ‘Lalbagh Cha Raja’ ganpati V/S VIP culture.

[Rishi Bagree @rishibagree]

Now even sports journalists are calling out Vinesh Phogat's lies.

Here are point-by-point rebuttals to Vinesh's lies which she peddling in political rallies in Haryana.

[Mr Sinha @Mrsinha]

J!hadi Engineer Rashid who was booked under UAPA for funding terrorists is granted bail by court just before J&K assembly elections.

First he was allowed to contest elections, won it, became an MP & now will roam freely. This is how ecosystem works!

[Shantanu Pendse @ShantanuPOnco]

..when taxpayers sponsoring your preparation and everything..you are accountable for even a gram of extra weight..

[BALA @erbmjha]

Kuchh bolunga toh vivad ho jayega!