https://t.co/Wv14KErbq7
So much of our field is rife with trials like these- from renal cancer to lung cancer to myeloma. Low resource countries are exploited to gain approval in the US. Such a good read- couldn’t agree more @JackWestMD @AaronGoodman33 @VPrasadMDMPH
@tobyeyre82@TheEBMT Glad EBMT did it since this was one of my CIBMTR proposals to look at auto SCT in PTLD ! It’s important and unique patient population!
Landmark paper 🚨: “decline in IGF1 has been considered ‘nature’s way of sustaining the aging individual’.. [their] work supports that these beneficial systemic effects come as a trade-off for robust function of certain tissue (incl. 🩸) stem cells” https://t.co/RDHlfqodaj
1/2 A really nice paper about estimands and intercurrent events, but I fear that estimands has come to mean throwing a lot of sensitivity analysis at the problem and avoid counting what matters to patients in the primary analysis. https://t.co/B5ftiwuhDd
@AaronGoodman33 No data to support either way unfortunately, the recommendations from expert opinions to give few cycles before sct came because most of MDS pts get RIC not MAC