Sherif Bayoumy

Postdoc ➡️

[الأهرام AlAhram @AlAhram]

أخيرا «ألزهايمر» يفقد قســوة المفاجأة..
د. شريف بيومى الباحث بجامعة أمستردام الـحرة: توصلنا لبروتين فى الدم يتوقع الإصابة بالمرض قبل ظهور الأعراض بـ20 عاما
https://t.co/3aInr4Ev08

[Sherif Bayoumy @Sherif_Bay]

@OskarHansson9 Thanks for your question, Oskar! These ELISAs weren’t sensitive enough for serum analysis, but as far as I know, @ADxNeuro has since transferred the assays to the Simoa platform for detecting beta-synuclein in serum

[Sherif Bayoumy @Sherif_Bay]

Excited to share the results of our latest work on Alzheimer’s disease biomarkers! Together with the team at ADx NeuroSciences, we developed two novel CSF assays for β-synuclein, each targeting a different region of the protein. https://t.co/gqBvIxXCDk

[Sherif Bayoumy @Sherif_Bay]

Thanks to all co-authors and my supervisors who made this possible!

[Sherif Bayoumy @Sherif_Bay]

Both reliably detect early synaptic degeneration across the Alzheimer’s continuum, and interestingly, the mid-region assay may even help distinguish disease stages.
If you're working on synaptic biomarkers, early AD detection, or assay development, this might be for you.

[Thomas K. Karikari @TommyKakari]

Two papers in two days for the #KarikariLab. Paper 1 gives guidelines for blood biobanking to support biomarker studies. Paper 2 reports association of plasma biomarkers with baseline cognition & longitudinal change in the population-based MYHAT study. @PittPsychiatry @PittADRC

[AD/PD - Advances in Science & Therapy @adpdnet]

A huge congratulations to all of the Junior Faculty Awardees!🎉👏🏻 #ADPD2024

[Sherif Bayoumy @Sherif_Bay]

I am grateful to the co-first author Giovanni Bellomo, Prof. Lucilla Parnetti and Prof. Charlotte Teunissen and all coauthors for making this project possible. A special thanks to @Fujirebio and @MIRIADE10 for their support!

[Sherif Bayoumy @Sherif_Bay]

Fully automated measurement of plasma Aβ42/40 and p‐tau181: Analytical robustness and concordance with cerebrospinal fluid profile along the Alzheimer's disease continuum in two independent cohorts - Bellomo - Alzheimer's & Dementia - Wiley Online Library https://t.co/5TMZyWVNzX

[Sherif Bayoumy @Sherif_Bay]

Here are the main results:

- The analytical performance of automated plasma determinations of Ab42/40 and p-tau181 was excellent.

- Renal dysfunction was associated with increased levels of p-tau181, p-tau181/Ab42 but not Ab42/40...

[Sherif Bayoumy @Sherif_Bay]

- Probabilistic models allowed very high accuracy in classifying patients with AD.

[Sherif Bayoumy @Sherif_Bay]

- Plasma Ab42/40 accurately reflected CSF A status, regardless of clinical diagnosis and stage of AD. - Plasma p-tau181 accurately reflected A+/T+ (not T) status in patients with MCI-AD and AD-dem but not in preclinical subjects ..

[Sherif Bayoumy @Sherif_Bay]

@cclm_degruyter @degruyter_pub @EMA_News Our study not only delves into NfL as an SMA biomarker but also provides normal reference ranges for serum NfL in a cohort of 240 neurologically healthy children.

[Sherif Bayoumy @Sherif_Bay]

I am thrilled that our review article on using Neurofilament Light Protein (NfL) as a biomarker for treatment monitoring in #SMA is now published in @cclm_degruyter. Thanks to all coauthors!
https://t.co/Cgo2kHjf9i @degruyter_pub

[Sherif Bayoumy @Sherif_Bay]

@cclm_degruyter @degruyter_pub This marks a milestone and adds to the visibility of our successful application which resulted in the issuance of a letter of support from the @EMA_News for the use of NfL in childhood neurological diseases. https://t.co/Xm5G8D1FBY

[Sherif Bayoumy @Sherif_Bay]

Neurofilament light protein as a biomarker for spinal muscular atrophy: a review and reference ranges - Read on https://t.co/Cgo2kHjf9i @degruyter_pub

[The Spectator Index @spectatorindex]

BREAKING: Al Arabiya reports there are over 800 casualties, between dead and injured, at the Al-Ahli Baptist Hospital.

[MIRIADE @MIRIADE10]

The final MIRIADE training week is well underway!

Our students receive training on grants waiting, personal career development and entrepreneur skills among others and are actively engaged with the sessions.

[Sherif Bayoumy @Sherif_Bay]

Impressive talk about dementia in Africa #AAIC2023

[RikOssenkoppele @RikOssenkoppele]

Great to learn about the epidemiology of Alzheimer’s disease in Africa from Adesola Ogunniyi. #AAIC23