At our best infectious diseases experts can act as the synapses that connect surgeons, internists, pharmacists, microbiologists, epidemiologists and the patients to make good decisions.
@ShipraGoelMD@JHMed_ID@VeroDioverti we were just being playful with each other. Of course, we will see everyone as soon as possible and are very happy to help our colleagues and patients.
"Crude 30-day mortality following a positive COVID-19 test was 2.2% in 2020, then decreased before stabilizing to 0.8%–1.0% from 2023 onward." Some people forget just how bad COVID was back then. https://t.co/Lqf8aJfHek~
Triazole-resistant Aspergillus fumigatus in the Netherlands between 1994 and 2022: a genomic and phenotypic study - The Lancet Microbe https://t.co/gDpqVmfLDu
@Bastards_Boston This team is starting to develop an identity and Duran is part of that. Players who can hit, run, play solid, defense (or are working on improving it), don't give up, and have an aggressive streak.
Aspergillus tanneri fast facts: Tends to be resistant to multiple antifungal agents, described in people with chronic granulomatous disease (CGD) Western parts of US, living in Western parts of the US. Disseminated and contiguous disease patterns
Clinical situation: should you use vancomycin as part of empiric therapy in patient with AML and pneumonia.
Answer from clinical trial: Not typically, if MRSA screen is negative - Talagtag - 2021 - Transplant Infectious Disease - Wiley Online Library https://t.co/N8HihhP6oA
@ross_prager Yes, but... medica school and residency and some fellowships, can be unforgivingly hard. So, it is ok to give yourself a break if you can't be happy during stretches of this time
Candida auris: a) adheres to skin and inanimate objects, b) colonization often clinically significant (compared to C. albicans), c) associated with outbreaks, d) often resistant to fluconazole, and sometimes echinocandins too. A good review article by Lionakis in NEJM in 2024
Teaching case: middle aged man with ulcerative colitis. Disease has been stable, but now seemingly flares. CMV viral load ~100K. Endoscopy: CMV colitis. CMV IgG had been negative previously. Now CMV IgM+. This is probably primary CMV infection with tissue invasive disease
For a patient in whom there is a high pre-test probability for Clostridium difficile infection: a positive C difficile PCR with a negative EIA for toxin, does not rule out C difficile. False negative tests for the EIA toxin do occur.
more about this organism and the skin
Seroy J, Antiporta P, Grim SA, Proia LA, Singh K, Clark NM. Aspergillus calidoustus case series and review of the literature. Transpl Infect Dis. 2017 Oct;19(5). doi: 10.1111/tid.12755. Epub 2017 Sep 19. PMID: 28741738.
Aspergillus calidoustus. I have seen it have a tendency for cutaneous involvement. Tends to be resistant to azoles. Here is another one from the literature. https://t.co/CFaGe9mrQY.
Thank you to today’s panel of MMI Thursday Seminar presenters — David Sullivan, MD, & our guests from @HopkinsMedicine moderator Dan Hanley, MD, @ShohamTxID, Nicole McBee & Karen Lane! Great interactive discussion about their multi-center #COVID-19 clinical trial