Shorter Lab Members

We are a group of scientists @Penn working to combat protein misfolding as a way to understand and treat neurodegenerative diseases. (student run)

[ShorterLab @ShorterLab]

Happy holidays from the Shorter lab!

[Aggregate @AggregateOA]

Early View💡
"A dual-functional BODIPY-based molecular rotor probe reveals different viscosity of protein aggregates in live cells" by He Huang, Yu Liu & Xin Zhang et al. @kfzhangxin @dicp_cas @Wiley_Chemistry #BODIPY #viscosity #protein #aggregate

Check👉https://t.co/i1sZ7Btumz

[Shorter Lab Members @ShorterLabGroup]

Multi‐Step Molecular Mechanism of Amyloid‐Like Aggregation of Nucleic Acid‐Binding Domain of TDP‐43 https://t.co/mxn9XprIkT

[Shorter Lab Members @ShorterLabGroup]

Human J-Domain Protein DnaJB6 Protects Yeast from [PSI+] Prion Toxicity https://t.co/19uoftRhiH

[🔬 R-loop @R_loop_papers]

Roles of RNA-binding proteins in neurological disorders, COVID-19, and cancer https://t.co/yqNur76f4A

[ShorterLab @ShorterLab]

Multivalency ensures persistence of a +TIP body at specialized microtubule ends: https://t.co/1Swi8V8wxg

[ShorterLab @ShorterLab]

Mechanisms of DNA opening revealed in AAA+ transcription complex structures: https://t.co/GqsEGiVcn6

[Shorter Lab Members @ShorterLabGroup]

A fond *fare*well to Dr.@CharlotteFare! We are excited to see what you do next @HopkinsMedicine 👩‍🔬✨

[Shorter Lab Members @ShorterLabGroup]

@HAntonicka you can download the submitted version with an Elsevier account

[Shorter Lab Members @ShorterLabGroup]

FUNDC1 Promotes Mitochondrial Translocation of TDP-43 and Modulates TDP-43 Induced Neurotoxicity https://t.co/rBR5vpMUOj

[UMich Diversity @UMichDiversity]

Kyla McMullen, the only Black American woman who has earned a PhD in computer science and engineering from U-M, has launched Modern Figures, a podcast that elevates the voices of Black women in computing. https://t.co/QzNFVnGAdY | #UMichDEI

[YingZhu @NanoPOTS_SCP]

I am excited to share I have formally joined Genentech as Senior principal scientist and group lead of #singlecell and #spatialproteomics. We have several positions opening now. Dear friends, please help to spread the messages. https://t.co/pf06O9fMeG

[Nature Reviews Drug Discovery @NatRevDrugDisc]

Amyotrophic lateral sclerosis: a neurodegenerative disorder poised for successful therapeutic translation https://t.co/7uwabmOcc9

This new review covers insights into the pathophysiology of ALS, advances in disease modelling, the current landscape of clinical trials and more

[Nat Rev Neurology @NatRevNeurol]

Proteomic clusters underlie heterogeneity in preclinical Alzheimer’s disease progression https://t.co/lHOXFDqCGZ

[Sabareesan A T @ATsabareesan]

(1/1) Proudly present our recent work on small molecule partitioning into Biomolecular condensates.

https://t.co/hlRUXw16UN

[JSDavis @jscdavis]

Attn: #HBCU #MSI faculty and trainees! Join us on January 12, 2023, for a hybrid presentation of how to bring cryoEM to your lab/institution, start a new collaboration or send your samples to one of the national cryoEM centers. @BlackinBiophys

[Research Trainee Affairs at Penn Medicine @RTAatPennMed]

Attn: Undergrads! Interested in biomed research? @PennMedicine offers an immersive summer research program #PennSUIP & a fantastic post-bacc program #PennPrep! 🔬🧬 To learn more, join us 1/12/23 (12-1p ET) or 1/16/23 (6-7p ET): https://t.co/dEeuKzFMIK #phdchat @IDEAL_research

[ShorterLab @ShorterLab]

Multivalent interactions facilitate motor-dependent protein accumulation at growing microtubule plus-ends: https://t.co/ThDxivQBnz

[Basir's Protein Assembly Lab @Basirsa]

Very pleased that our paper "Mechanistic insights into monomer level prevention of amyloid aggregation" is online now. https://t.co/RusrlkMGWF