Henrik Siboni

Biophysicist in Pharmacy 💊
PhD Candidate 👨‍🔬 at the @UniGraz 🇦🇹 in @LGrillGroup and pharmaceutical technology 👀
What is happening?👂

[Henrik Siboni @SiboniHenrik]

The @NatureNano paper from @OxfordChemistry says that microparticles in water can aggregate if they are negatively charged. Normally, electrostatic repulsion helps stabilize a colloidal suspension 🧪

Should consider this when developing nanoscale drug delivery systems? 🤔

[Henrik Siboni @SiboniHenrik]

Did you know that you can study uptake and efficacy with #cellmechanics? Read about it in our new review paper in @MDPIpharma. Thanks a lot to my co-authors and @LGrillGroup (@UniGraz) 🙌

Do you think that this will become an industry standard or are there better methods? 🤔

[Pharmaceutics MDPI @MDPIpharma]

Do you use #cellmechanics in pharmaceutics? This
@UniGraz team writes how to use #AFM to track stiffness and rheology of cells upon drug treatment including interpretations for uptake, toxicity, and efficacy🧫

Read the paper: https://t.co/oapTfIpNll
@LGrillGroup @SiboniHenrik

[Henrik Siboni @SiboniHenrik]

Not so often I learn about organic chemistry 😬 Apparently, it has been very difficult to use alcohols to synthesize other molecules 🧪

[Henrik Siboni @SiboniHenrik]

My colleague Grant is in Scientific American! 😮

[Henrik Siboni @SiboniHenrik]

Apparently, there are cases where soluble drugs undergo a phase transition where they become less soluble and effective 😮💊

[Henrik Siboni @SiboniHenrik]

💚

[Henrik Siboni @SiboniHenrik]

My colleague David presented a paper from @CEITEC_Brno where he was for his bachelor 📝
They have a very wide selection of equpiment including combined Raman and atomic force microscopy, cryo-electron microscopy, magnetic resonance imaging, and electroencephalography 🔬

[Henrik Siboni @SiboniHenrik]

Fun hosting journal club 🥧

Kinesin uses 1 ATP/step as fuel to transport cargo along microtubuli 🚚

@StefanHellLabs investigated when ATP is bound 🛢️

@TakahiroDeguch1 observed kinesin blocked in its path and jumping microtubuli 🛣️

Question from the club: How does it jump? 🤔

[Henrik Siboni @SiboniHenrik]

My colleague @bensuben_ presented at the journal club today 💪

[Henrik Siboni @SiboniHenrik]

The audience played along at the Styrian Science Slam 2023🔬

Big thanks to all participants, the audience, fellow performers ❤️ and of course the organizer Bernhard! 💪

I highly recommend it to other scientists! 🤹‍♂️

Photo: SHK/Jimmy Lunghammer #ScienceSlam #PublicEngagement

[Henrik Siboni @SiboniHenrik]

They suggest that it can be used for periodic drug delivery 🤔💊

[Henrik Siboni @SiboniHenrik]

Journal Club on nanochannels today 👀

[Henrik Siboni @SiboniHenrik]

New Nature paper by my colleague Grant ❤️🥳

[nature @Nature]

Nature research paper: Adsorbate motors for unidirectional translation and transport https://t.co/crOtS3SEDL

[nature @Nature]

Nature research paper: Adsorbate motors for unidirectional translation and transport https://t.co/crOtS3SEDL

[Henrik Siboni @SiboniHenrik]

Does corrosion affect the environmental safety of pipelines? 🤔 #fridayAFM

Find out in this study from Lhiam Paton in the group of Jörg Feldmann at @UniGraz where I measured the surface roughness and area 👨‍🔬

Thanks for a nice collaboration 😊

https://t.co/mEz8FLjVUQ

[Henrik Siboni @SiboniHenrik]

@HCorteLeo Hm, actually not 🤔 But marcipan candy is much harder and probably close to equilibrium with the moisture in the air. If you let your leaf dry for a day, I think that you would see less drift 🍃

[Henrik Siboni @SiboniHenrik]

Trying my hand at science outreach on my Instagram account - check it out 😊

#fridayAFM
#outreach

https://t.co/kwUEy47GpU

[Henrik Siboni @SiboniHenrik]

@HCorteLeo Thanks 😃 No surface preparation, I wanted to look at the untouched surface fresh from the bag 🍬 The roughness is generally too large, but you can find smaller areas that are flat enough to measure 🔍

[Bensu @bensuben_]

#qPlusforChris !! 😂

[Henrik Siboni @SiboniHenrik]

What happens when you add citric acid 🍋 to your nanoscale drug delivery system? 💊 Find out from our new paper in @MDPIpharma! 👨🏼‍🔬
https://t.co/ilVFejyclY

#AFM #Pharmacy #PharmaceuticalTechnology #AtomicForceMicroscopy #nano