Simon John Lab

Our lab investigates molecular features of #glaucoma @Columbia . Tweets from members of the lab.

[Simon John Lab @SimonJohnLab]

New Nature Communications paper:
Elevated IOP causes vein-specific BRB breakdown in glaucoma, associated with MFSD2A loss and increased endothelial transcytosis. Stabilizing endothelial β-catenin reduced leakage and mitigated neurodegeneration.

https://t.co/wPuPN4FdEU

[Simon John Lab @SimonJohnLab]

🧐New study: pyruvate and related metabolites may boost resilience to glaucoma in individuals with high genetic risk. Read the article here: https://t.co/zdRFORWZ1p

[Simon John Lab @SimonJohnLab]

This article was just published in Nature Communications. Congrats, @cubical and @SimonJohnLab! Hard work pays off! https://t.co/LwbdZlRF1d

[Simon John Lab @SimonJohnLab]

👁️Our latest preprint is out! We reveal an exciting, previously overlooked mechanism contributing to glaucoma pathogenesis: IOP-induced blood-retinal barrier breakdown. Check it out here: https://t.co/XeBXbR76NA

[Simon John Lab @SimonJohnLab]

🚨📜Check out our latest preprint: "TLR4 deficiency does not alter glaucomatous progression in a mouse model of chronic glaucoma" https://t.co/1jeeKM1FMj

[cubical/kizhatil @cubical]

Paper Alert- new preprint dropped- awesome collab with @LadyGlaucoma and @SimonJohnLab - multimodal sequence profiling of the mouse #Schlemmscanal and more-tweetorial to follow!!

https://t.co/HRWCCp1SAl

[Simon John Lab @SimonJohnLab]

The Department of Ophthalmology is seeking a Staff Associate to work in a dynamic experimental genetics laboratory at Columbia University with duties at the Manhattanville campus. The laboratory focuses on the genetics, pathophysi…https://t.co/MeWiAR1F4q https://t.co/mpKxK7vIma

[Simon John Lab @SimonJohnLab]

I’m #hiring. Know anyone who might be interested? https://t.co/RHoRlKUhA9

[Simon John Lab @SimonJohnLab]

The John Lab is #hiring ! Check out our Research Associate I posting and come work with us at Columbia University: https://t.co/SKNAFj9ALR

Please RT

[Simon John Lab @SimonJohnLab]

The John Lab is #hiring ! Check out our *updated* Research Associate posting and come work for us at Columbia University:
https://t.co/fkiaW2j8OA
Please RT.

[Simon John Lab @SimonJohnLab]

The John Lab is #hiring ! Check out our *updated* Colony Manager posting and come work for us at Columbia University:
https://t.co/0GJ3z32jy7
Please RT.

[Simon John Lab @SimonJohnLab]

@Asim10885531 Asim, I would love to hear from you. Please apply at https://t.co/VRH8flKpQI

[Simon John Lab @SimonJohnLab]

The John lab is hiring! 2 Research Associate positions available. Come work with us in Columbia University. For more info, to apply: https://t.co/VkMCYat0PB . https://t.co/ykk4q7Jzve
Please RT.

[Simon John Lab @SimonJohnLab]

What we do: Cool glaucoma research. What we need: Dedicated and motivated applicants. What we offer: A competitive salary, training, mentorship, and a boost to your career.

[Simon John Lab @SimonJohnLab]

The John lab is hiring a mouse colony manager! Come work for us at Columbia in vibrant NYC. The position will provide exposure and training in areas including mammalian genetics, neuroscience, molecular biology, and physiology! For more info, to apply: https://t.co/VRH8flKpQI

[Simon John Lab @SimonJohnLab]

Another recent publication: https://t.co/U0ch639EU7
Study led by Nick Tolman identifies differential vulnerability to glaucoma in Lmx1b mutant mice.

[Simon John Lab @SimonJohnLab]

Highlighting recent publications from our lab: https://t.co/OUbANnkNQP
An excellent study led by @pete_the_teapot and Jeff Harder on disturbed metabolism in glaucoma and protection by rapamycin.