Simran Samra

PhD Candidate at BC Children's Hospital Research Institute
University of British Columbia

[Casanova Lab @casanova_lab]

A surprising and exciting observation !
Human germline biallelic loss-of-function OSMR variants cause severe allergic disease https://t.co/BFzcoq1Tyo

[Turvey lab @TurveyLab]

New human inborn error of immunity!
By identifying biallelic OSMR deficiency as a novel Primary Atopic Disorder, we uncover a previously unrecognized mechanism driving severe allergic disease and provide new insights into the biology of human atopy.

[Journal of Human Immunity @jhumimmunity]

New human primary atopic disorder defined: @SimranKaurSamra and Sharma et al. @turveylab @UBC show OSMR deficiency disrupts OSM-STAT signaling, driving severe early-onset #eczema, #eosinophilia, and elevated IgE. https://t.co/2hdpZwogkP

#Immunology #Genetics #Atopy #IEIs

[Turvey lab @TurveyLab]

https://t.co/oDzouvN9QI

[Turvey lab @TurveyLab]

Rare children's genetic disease found in B.C. - Vancouver Is Awesome https://t.co/ALzHKSaN3s

[Turvey lab @TurveyLab]

New rare disease discovered in teen brothers at BC Children’s Hospital | https://t.co/xR1hcNV9eD https://t.co/GKi2FElmeE

[Turvey lab @TurveyLab]

@TurveyLab has branched out into neurodevelopment with this new preprint linking gene changes in MARK4 to pediatric neurodevelopment!

Led by PhD student Simran Samra.

@CatherineMBiggs @vaseghi_maryam @_areeshasalman @bhavi_modi_