Springer Pathology

Tweets on all aspects of Springer’s Pathology publishing program. Check out this space for free to read articles, upcoming conferences and much more..

[Springer Pathology @SpringerPath]

Virchows Archiv reports on ten cases of low-grade fibromyxoid sarcoma (LGFMS) at acral sites, primarily affecting young individuals. Tumors were located in the foot and hand, highlighting the need for awareness of this rare condition.

https://t.co/JKhBF6CGbG

[Springer Pathology @SpringerPath]

A study identifies high-grade renal tumors linked to FLCN mutations, characterized by aggressive features and varied growth patterns. The findings highlight the need for FLCN testing in cases resembling high-grade papillary RCC.

https://t.co/fhKcZmSmRi

[Springer Pathology @SpringerPath]

Virchows Archiv reports on five cases of cDC sarcoma coexisting with acute myeloid leukemia (AML) or myelodysplastic neoplasm. Histological subtypes included Langerhans cell sarcoma and malignant indeterminate dendritic cell tumor.

https://t.co/khHPXl5ozL

[Springer Pathology @SpringerPath]

38th European Congress of Pathology - Abstracts

https://t.co/Z0OrHJjAb2

[Springer Pathology @SpringerPath]

Virchows Archiv outlines a framework for integrating AI into pathology labs, focusing on local verification and governance for safe clinical use. This approach emphasizes the need for tailored strategies based on AI application types.

https://t.co/RwOKLQuaYl

[Springer Pathology @SpringerPath]

Virchows Archiv documents a case of a 28-year-old man with a slowly enlarging intramuscular mass in the neck. Imaging revealed a well-circumscribed mass with calcifications, prompting further histologic examination.

https://t.co/BYcDs8Yv3b

[Springer Pathology @SpringerPath]

Virchows Archiv reports on a case of a 74-year-old man with a thyroid mass showing loss of TTF1 and PAX8 expression, raising concerns for metastatic disease. Accurate diagnosis is crucial as treatment strategies vary significantly.

https://t.co/QZehZHhELD

[Springer Pathology @SpringerPath]

A study in Virchows Archiv compares pancreatic ductal adenocarcinomas (PDAC) linked to intraductal papillary mucinous neoplasms (I-PDAC) with those not associated (NI-PDAC) and finds I-PDACs often diagnosed at earlier stages.

https://t.co/65xaLsIAIj

[Springer Pathology @SpringerPath]

A cohort of 25 patients with FET::TFCP2 fusion reveals that these tumors often exhibit myogenic differentiation and genomic instability, with 40% showing amplifications in receptor tyrosine kinase pathways and cell cycle-related genes.

https://t.co/ukva0JJ3sg

[Springer Pathology @SpringerPath]

Virchows Archiv highlights a shift in diagnosing hepatocellular adenoma (HCA) and hepatocellular carcinoma (HCC) from traditional morphology to advanced morpho-molecular analysis, enhancing classification accuracy and patient care.

https://t.co/mTcVIjxjpm

[Springer Pathology @SpringerPath]

Analysis of Merkel cell carcinoma cases showed that skeletal muscle invasion is linked to a higher frequency of Merkel cell polyomavirus positivity in head and neck tumors, suggesting a potential connection worth further investigation.

https://t.co/I1kS9ShiMq

[Springer Pathology @SpringerPath]

Findings in Virchows Archiv evaluates various grading methods for pulmonary adenocarcinomas, analyzing their impact on overall survival and recurrence-free survival in 304 patients from Szeged between 2010 and 2016.

https://t.co/ctbOt29tdh

[Springer Pathology @SpringerPath]

The article outlines the evolution of IBD-associated dysplasia classification, culminating in the WHO's 6th edition. It addresses inconsistencies in terminology and emphasizes the importance of standardized reporting for effective clinical management.

https://t.co/iPxoscURyv

[Springer Pathology @SpringerPath]

A study in Virchows Archiv examines lung allograft biopsies, revealing that acute cellular rejection and lymphocytic bronchiolitis have unique immune cell compositions. This may improve diagnostic accuracy against similar conditions like infection.

https://t.co/o45uyKKQJ1

[Springer Pathology @SpringerPath]

Virchows Archiv reports on a study validating a custom NGS panel for thyroid pathology. The panel was tested on cancer cell lines, FFPE tissues, and FNA samples, achieving a 100% success rate for histological material.

https://t.co/XIKL9IRKZY

[Springer Pathology @SpringerPath]

A study in VIAR assessed inter-pathologist agreement on HER2-negative invasive breast carcinomas, analyzing 125 excisions & 78 biopsies. Findings indicate substantial reproducibility but moderate intra-tumor agreement, highlighting diagnostic challenges.
https://t.co/WWWXZtuqwx

[Springer Pathology @SpringerPath]

A retrospective analysis of 165 patients with high-risk prostate cancer reveals that combining ISUP GG and IDC-P status enhances prediction accuracy for clinical recurrence post-IMRT, achieving an AUC of 0.850 with key pathological features.

https://t.co/WxIanYgSi8

[Springer Pathology @SpringerPath]

Virchows Archiv discusses the role of liquid biopsy (LBx) in solid tumors, emphasizing plasma ctDNA analysis as a minimally invasive method that complements traditional tissue analysis when samples are limited or outdated.

https://t.co/gYoBE3GyRM

[Springer Pathology @SpringerPath]

The Journal of Hematopathology reports a case of high-grade B-cell lymphoma, not otherwise specified (HGBCL-NOS), misdiagnosed as T-cell lymphoma due to unusual antigen expression. This highlights diagnostic challenges in aggressive B-cell neoplasms.

https://t.co/y5OAPFDZhU

[Springer Pathology @SpringerPath]

A case study in Head and Neck Pathology details an inflammatory rhabdomyoblastic tumor (IRMT) in a 67-year-old man, showing malignant progression despite its typically indolent nature. The tumor was located in the left sternocleidomastoid muscle.

https://t.co/zr2hZjjWaH