A mucosal #antibody called #SIgA can bind to bacterial surface proteins, triggering an immune response to improve infection outcomes. But these interactions are poorly understood.
Although the role of antibodies is universal, the structure varies in different animals. In a new study, researchers analyzed the antibody Immunoglobulin M in rainbow trout to shed some light on why these proteins have evolved over time.
Learn more at https://t.co/kqG7HfBKto.
Happy to share our labs new publication detailing the structure of IgM from fish. Great work by graduate student Mengfan (Iris) Lyu and @DrAndreyM! #IgM#CryoEM
https://t.co/Phe2eG09sS
Happy to share the latest preprint from the @StadtmuellerLab - an incredible effort by recent PhD student @Sonya31397350! Engineered Secretory Immunoglobulin A provides insights on antibody-based effector mechanisms targeting Clostridiodes difficile https://t.co/oRKW4aeKPe
Happy to share recent work from the @StadtmuellerLab published today in Nature Communications! Great effort by recent graduate Qianqiao (Heather Liu)! #IgA#antibodies#CryoEM
https://t.co/GtiKImugfy
Thrilled to introduce Dr. Qianqiao (Heather) Liu, the first PhD graduate from the Stadtmueller Lab! Congrats Heather!!! We wish you well on your next adventure in the @the_sharaf_lab@Stanford !
@StadtmuellerLab & Qianqiao (Heather) Liu shared how cryoEM training & access at NIH sponsored national centers helped investigate polymeric antibodies.
The talk will be posted soon at https://t.co/jDUXmzIZI4
Access #cryoEM resources at no cost: https://t.co/1I1pTYo7Q7
Our new manuscript, in collaboration with the Bassik Lab, is out on bioRxiv. After much screening, new CRISPRi (better KRAB) and especially better CRISPRa=dCas9-NFZ (with an ancient KRAB!): https://t.co/LWfQudZQDX
Happy to share a new preprint from the Stadtmueller Lab; great effort by graduate student Qianqiao Liu!
The Structures of Secretory IgA in complex with Streptococcus pyogenes M4 and human CD89 provide insights on mucosal host-pathogen interactions https://t.co/wKHcehy9ZX
🦠 Revenge of the Microbes 🦠
Congratulations to Dr. Brenda Wilson (Dept. of #Microbiology) on her new book!! 🎉🎉
📗 Check out Wilson's interview with MCB about her ongoing investigation into our war against #pathogens: https://t.co/TlyKlbpHOn
#scicomm#academicwriting
I am very excited for this new start at the department of Microbiology at UChicago @UChicago_Micro ! Thanks to everyone for their help and support throughout the whole process. I’m building up a team so if you are interested please don’t hesitate to contact me.
Happy to share a new preprint from the Stadtmueller Lab! #Antibodies#cryoEM#IgM
The structure of the teleost Immunoglobulin M core provides insights on polymeric antibody evolution, assembly, and function https://t.co/Ww77SoiQsT
The Stadtmueller Lab had a great time sharing and learning new science at the the West Coast Structural Biology Workshop last week! Many thanks to @Yeates_Lab, @OchoaJessicaM, Jose Rodriguez, and Pascal Egea for organizing! #StructuralBiology#WCSBW2023
We were fortunate to have Prof Beth Stadtmueller of @StadtmuellerLab and Prof Collin Kieffer visit our lab to share their amazing research since leaving the Bjorklab. We hope you will visit again, and just maybe SoCal will be a little sunnier next time ☀️
REALLY excited about this opportunity from #HHMI to investigate and engineer avian and human antibody responses to influenza with a wonder team: @GuthmillerJenna, @wchnicholas, @angadmehta, and Wilfred van der Donk! @HHMINEWS
STORY: https://t.co/4Xa1cZGwav